Radaszkiewicz T - Search Results

1

Mutations in GRK2 cause Jeune syndrome by impairing Hedgehog and canonical Wnt signaling.

Bosakova M, Abraham SP, Nita A, Hruba E, Buchtova M, Taylor SP, Duran I, Martin J, Svozilova K, Barta T, Varecha M, Balek L, Kohoutek J, Radaszkiewicz T, Pusapati GV, Bryja V, Rush ET, Thiffault I, Nickerson DA, Bamshad MJ; University of Washington Center for Mendelian Genomics; Rohatgi R, Cohn DH, Krakow D, Krejci P. Bosakova M, et al. Among authors: radaszkiewicz t. EMBO Mol Med. 2020 Nov 6;12(11):e11739. doi: 10.15252/emmm.201911739. Epub 2020 Oct 14. EMBO Mol Med. 2020. PMID: 33200460 Free PMC article.

2

Asymmetry of VANGL2 in migrating lymphocytes as a tool to monitor activity of the mammalian WNT/planar cell polarity pathway.

Kaucká M, Petersen J, Janovská P, Radaszkiewicz T, Smyčková L, Daulat AM, Borg JP, Schulte G, Bryja V. Kaucká M, et al. Among authors: radaszkiewicz t. Cell Commun Signal. 2015 Jan 28;13:2. doi: 10.1186/s12964-014-0079-1. Cell Commun Signal. 2015. PMID: 25627785 Free PMC article.

3

A Novel Role for the BMP Antagonist Noggin in Sensitizing Cells to Non-canonical Wnt-5a/Ror2/Disheveled Pathway Activation.

Bernatik O, Radaszkiewicz T, Behal M, Dave Z, Witte F, Mahl A, Cernohorsky NH, Krejci P, Stricker S, Bryja V. Bernatik O, et al. Among authors: radaszkiewicz t. Front Cell Dev Biol. 2017 May 4;5:47. doi: 10.3389/fcell.2017.00047. eCollection 2017. Front Cell Dev Biol. 2017. PMID: 28523267 Free PMC article.

4

The N-Terminal Part of the Dishevelled DEP Domain Is Required for Wnt/β-Catenin Signaling in Mammalian Cells.

Paclíková P, Bernatík O, Radaszkiewicz TW, Bryja V. Paclíková P, et al. Mol Cell Biol. 2017 Aug 28;37(18):e00145-17. doi: 10.1128/MCB.00145-17. Print 2017 Sep 15. Mol Cell Biol. 2017. PMID: 28674183 Free PMC article.

5

The natural compound Jatrophone interferes with Wnt/β-catenin signaling and inhibits proliferation and EMT in human triple-negative breast cancer.

Fatima I, El-Ayachi I, Taotao L, Lillo MA, Krutilina RI, Seagroves TN, Radaszkiewicz TW, Hutnan M, Bryja V, Krum SA, Rivas F, Miranda-Carboni GA. Fatima I, et al. PLoS One. 2017 Dec 27;12(12):e0189864. doi: 10.1371/journal.pone.0189864. eCollection 2017. PLoS One. 2017. PMID: 29281678 Free PMC article.

6

Casein kinase 1 is a therapeutic target in chronic lymphocytic leukemia.

Janovska P, Verner J, Kohoutek J, Bryjova L, Gregorova M, Dzimkova M, Skabrahova H, Radaszkiewicz T, Ovesna P, Vondalova Blanarova O, Nemcova T, Hoferova Z, Vasickova K, Smyckova L, Egle A, Pavlova S, Poppova L, Plevova K, Pospisilova S, Bryja V. Janovska P, et al. Among authors: radaszkiewicz t. Blood. 2018 Mar 15;131(11):1206-1218. doi: 10.1182/blood-2017-05-786947. Epub 2018 Jan 9. Blood. 2018. PMID: 29317454 Free article.

7

Dishevelled has a YAP nuclear export function in a tumor suppressor context-dependent manner.

Lee Y, Kim NH, Cho ES, Yang JH, Cha YH, Kang HE, Yun JS, Cho SB, Lee SH, Paclikova P, Radaszkiewicz TW, Bryja V, Kang CG, Yuk YS, Cha SY, Kim SY, Kim HS, Yook JI. Lee Y, et al. Nat Commun. 2018 Jun 12;9(1):2301. doi: 10.1038/s41467-018-04757-w. Nat Commun. 2018. PMID: 29895829 Free PMC article.

8

The planar cell polarity protein VANG-1/Vangl negatively regulates Wnt/β-catenin signaling through a Dvl dependent mechanism.

Mentink RA, Rella L, Radaszkiewicz TW, Gybel T, Betist MC, Bryja V, Korswagen HC. Mentink RA, et al. Among authors: radaszkiewicz tw. PLoS Genet. 2018 Dec 7;14(12):e1007840. doi: 10.1371/journal.pgen.1007840. eCollection 2018 Dec. PLoS Genet. 2018. PMID: 30532125 Free PMC article.

9

Dishevelled-3 conformation dynamics analyzed by FRET-based biosensors reveals a key role of casein kinase 1.

Harnoš J, Cañizal MCA, Jurásek M, Kumar J, Holler C, Schambony A, Hanáková K, Bernatík O, Zdráhal Z, Gömöryová K, Gybeľ T, Radaszkiewicz TW, Kravec M, Trantírek L, Ryneš J, Dave Z, Fernández-Llamazares AI, Vácha R, Tripsianes K, Hoffmann C, Bryja V. Harnoš J, et al. Among authors: radaszkiewicz tw. Nat Commun. 2019 Apr 18;10(1):1804. doi: 10.1038/s41467-019-09651-7. Nat Commun. 2019. PMID: 31000703 Free PMC article.

10

WNT signaling inducing activity in ascites predicts poor outcome in ovarian cancer.

Kotrbová A, Ovesná P, Gybel' T, Radaszkiewicz T, Bednaříková M, Hausnerová J, Jandáková E, Minář L, Crha I, Weinberger V, Záveský L, Bryja V, Pospíchalová V. Kotrbová A, et al. Among authors: radaszkiewicz t. Theranostics. 2020 Jan 1;10(2):537-552. doi: 10.7150/thno.37423. eCollection 2020. Theranostics. 2020. PMID: 31903136 Free PMC article.

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