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TREM1 disrupts myeloid bioenergetics and cognitive function in aging and Alzheimer disease mouse models.
Wilson EN, Wang C, Swarovski MS, Zera KA, Ennerfelt HE, Wang Q, Chaney A, Gauba E, Ramos Benitez JA, Le Guen Y, Minhas PS, Panchal M, Tan YJ, Blacher E, A Iweka C, Cropper H, Jain P, Liu Q, Mehta SS, Zuckerman AJ, Xin M, Umans J, Huang J, Durairaj AS, Serrano GE, Beach TG, Greicius MD, James ML, Buckwalter MS, McReynolds MR, Rabinowitz JD, Andreasson KI. Wilson EN, et al. Among authors: rabinowitz jd. Nat Neurosci. 2024 May;27(5):873-885. doi: 10.1038/s41593-024-01610-w. Epub 2024 Mar 27. Nat Neurosci. 2024. PMID: 38539014 Free PMC article.
Selected Ion Monitoring for Orbitrap-Based Metabolomics.
Lu W, McBride MJ, Lee WD, Xing X, Xu X, Li X, Oschmann AM, Shen Y, Bartman C, Rabinowitz JD. Lu W, et al. Among authors: rabinowitz jd. Metabolites. 2024 Mar 25;14(4):184. doi: 10.3390/metabo14040184. Metabolites. 2024. PMID: 38668312 Free PMC article.
Off-target depletion of plasma tryptophan by allosteric inhibitors of BCKDK.
Bowman CE, Neinast MD, Jang C, Patel J, Blair MC, Mirek ET, Jonsson WO, Chu Q, Merlo L, Mandik-Nayak L, Anthony TG, Rabinowitz JD, Arany Z. Bowman CE, et al. Among authors: rabinowitz jd. bioRxiv [Preprint]. 2024 Mar 10:2024.03.05.582974. doi: 10.1101/2024.03.05.582974. bioRxiv. 2024. PMID: 38496495 Free PMC article. Preprint.
Mitochondrial ATP generation is more proteome efficient than glycolysis.
Shen Y, Dinh HV, Cruz ER, Chen Z, Bartman CR, Xiao T, Call CM, Ryseck RP, Pratas J, Weilandt D, Baron H, Subramanian A, Fatma Z, Wu ZY, Dwaraknath S, Hendry JI, Tran VG, Yang L, Yoshikuni Y, Zhao H, Maranas CD, Wühr M, Rabinowitz JD. Shen Y, et al. Among authors: rabinowitz jd. Nat Chem Biol. 2024 Mar 6. doi: 10.1038/s41589-024-01571-y. Online ahead of print. Nat Chem Biol. 2024. PMID: 38448734
mTORC1 controls murine postprandial hepatic glycogen synthesis via Ppp1r3b.
Uehara K, Lee WD, Stefkovich M, Biswas D, Santoleri D, Garcia Whitlock A, Quinn W 3rd, Coopersmith T, Creasy KT, Rader DJ, Sakamoto K, Rabinowitz JD, Titchenell PM. Uehara K, et al. Among authors: rabinowitz jd. J Clin Invest. 2024 Jan 30;134(7):e173782. doi: 10.1172/JCI173782. J Clin Invest. 2024. PMID: 38290087 Free PMC article.
Reprogramming neuroblastoma by diet-enhanced polyamine depletion.
Cherkaoui S, Yang L, McBride M, Turn CS, Lu W, Eigenmann C, Allen GE, Panasenko OO, Zhang L, Vu A, Liu K, Li Y, Gandhi OH, Surrey L, Wierer M, White E, Rabinowitz JD, Hogarty MD, Morscher RJ. Cherkaoui S, et al. Among authors: rabinowitz jd. bioRxiv [Preprint]. 2024 Jan 8:2024.01.07.573662. doi: 10.1101/2024.01.07.573662. bioRxiv. 2024. PMID: 38260457 Free PMC article. Preprint.
296 results