Murine muscle cell models for Pompe disease and their use in studying therapeutic approaches.
Takikita S, Myerowitz R, Zaal K, Raben N, Plotz PH.
Takikita S, et al. Among authors: raben n.
Mol Genet Metab. 2009 Apr;96(4):208-17. doi: 10.1016/j.ymgme.2008.12.012. Epub 2009 Jan 22.
Mol Genet Metab. 2009.
PMID: 19167256
Free PMC article.
To evaluate substrate deprivation as a strategy to prevent the accumulation of lysosomal glycogen, we knocked down Atg7, a gene essential for autophagosome formation, via siRNA, but we observed no effect on the extent of glycogen accumulation, thus confirming our recent observati …
To evaluate substrate deprivation as a strategy to prevent the accumulation of lysosomal glycogen, we knocked down Atg7, a gene essential fo …