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Genotype-guided tamoxifen dosing increases active metabolite exposure in women with reduced CYP2D6 metabolism: a multicenter study.
Irvin WJ Jr, Walko CM, Weck KE, Ibrahim JG, Chiu WK, Dees EC, Moore SG, Olajide OA, Graham ML, Canale ST, Raab RE, Corso SW, Peppercorn JM, Anderson SM, Friedman KJ, Ogburn ET, Desta Z, Flockhart DA, McLeod HL, Evans JP, Carey LA. Irvin WJ Jr, et al. J Clin Oncol. 2011 Aug 20;29(24):3232-9. doi: 10.1200/JCO.2010.31.4427. Epub 2011 Jul 18. J Clin Oncol. 2011. PMID: 21768473 Free PMC article.
In vivo assessment of the metabolic activity of CYP2D6 diplotypes and alleles.
Hertz DL, Snavely AC, McLeod HL, Walko CM, Ibrahim JG, Anderson S, Weck KE, Magrinat G, Olajide O, Moore S, Raab R, Carrizosa DR, Corso S, Schwartz G, Peppercorn JM, Evans JP, Jones DR, Desta Z, Flockhart DA, Carey LA, Irvin WJ Jr. Hertz DL, et al. Among authors: raab r. Br J Clin Pharmacol. 2015 Nov;80(5):1122-30. doi: 10.1111/bcp.12665. Epub 2015 Aug 2. Br J Clin Pharmacol. 2015. PMID: 25907378 Free PMC article. Clinical Trial.
Tamoxifen Dose Escalation in Patients With Diminished CYP2D6 Activity Normalizes Endoxifen Concentrations Without Increasing Toxicity.
Hertz DL, Deal A, Ibrahim JG, Walko CM, Weck KE, Anderson S, Magrinat G, Olajide O, Moore S, Raab R, Carrizosa DR, Corso S, Schwartz G, Graham M, Peppercorn JM, Jones DR, Desta Z, Flockhart DA, Evans JP, McLeod HL, Carey LA, Irvin WJ Jr. Hertz DL, et al. Among authors: raab r. Oncologist. 2016 Jul;21(7):795-803. doi: 10.1634/theoncologist.2015-0480. Epub 2016 May 25. Oncologist. 2016. PMID: 27226358 Free PMC article.
Patients' understanding of how genotype variation affects benefits of tamoxifen therapy for breast cancer.
Brewer NT, Defrank JT, Chiu WK, Ibrahim JG, Walko CM, Rubin P, Olajide OA, Moore SG, Raab RE, Carrizosa DR, Corso SW, Schwartz G, Peppercorn JM, McLeod HL, Carey LA, Irvin WJ Jr. Brewer NT, et al. Among authors: raab re. Public Health Genomics. 2014;17(1):43-7. doi: 10.1159/000356565. Epub 2014 Jan 22. Public Health Genomics. 2014. PMID: 24457521 Free PMC article.
Implementing a personalized medicine cancer program in a community cancer system.
Dressler LG, Bell GC, Schuetze DP, Steciuk MR, Binns OA, Raab RE, Abernathy PM, Wilson CM, Kunutsor SE, Loveless MC, Ahearne PM, Messino MJ. Dressler LG, et al. Among authors: raab re. Per Med. 2019 May;16(3):221-232. doi: 10.2217/pme-2018-0112. Epub 2019 May 21. Per Med. 2019. PMID: 31109249 No abstract available.
178 results