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Clearance of senescent macrophages ameliorates tumorigenesis in KRAS-driven lung cancer.
Haston S, Gonzalez-Gualda E, Morsli S, Ge J, Reen V, Calderwood A, Moutsopoulos I, Panousopoulos L, Deletic P, Carreno G, Guiho R, Manshaei S, Gonzalez-Meljem JM, Lim HY, Simpson DJ, Birch J, Pallikonda HA, Chandra T, Macias D, Doherty GJ, Rassl DM, Rintoul RC, Signore M, Mohorianu I, Akbar AN, Gil J, Muñoz-Espín D, Martinez-Barbera JP. Haston S, et al. Cancer Cell. 2023 Jul 10;41(7):1242-1260.e6. doi: 10.1016/j.ccell.2023.05.004. Epub 2023 Jun 1. Cancer Cell. 2023. PMID: 37267953 Free article.
Controlled masking and targeted release of redox-cycling ortho-quinones via a C-C bond-cleaving 1,6-elimination.
Dunsmore L, Navo CD, Becher J, de Montes EG, Guerreiro A, Hoyt E, Brown L, Zelenay V, Mikutis S, Cooper J, Barbieri I, Lawrinowitz S, Siouve E, Martin E, Ruivo PR, Rodrigues T, da Cruz FP, Werz O, Vassiliou G, Ravn P, Jiménez-Osés G, Bernardes GJL. Dunsmore L, et al. Nat Chem. 2022 Jul;14(7):754-765. doi: 10.1038/s41557-022-00964-7. Epub 2022 Jun 27. Nat Chem. 2022. PMID: 35764792 Free PMC article.
Assessment of neuropsychological function in brain tumor treatment: a comparison of traditional neuropsychological assessment with app-based cognitive screening.
Romero-Garcia R, Owen M, McDonald A, Woodberry E, Assem M, Coelho P, Morris RC, Price SJ, Santarius T, Suckling J, Manly T, Erez Y, Hart MG. Romero-Garcia R, et al. Acta Neurochir (Wien). 2022 Aug;164(8):2021-2034. doi: 10.1007/s00701-022-05162-5. Epub 2022 Mar 1. Acta Neurochir (Wien). 2022. PMID: 35230551 Free PMC article.
Cellular senescence in cancer: from mechanisms to detection.
Ou HL, Hoffmann R, González-López C, Doherty GJ, Korkola JE, Muñoz-Espín D. Ou HL, et al. Mol Oncol. 2021 Oct;15(10):2634-2671. doi: 10.1002/1878-0261.12807. Epub 2020 Oct 22. Mol Oncol. 2021. PMID: 32981205 Free PMC article. Review.
Role of RNA modifications in cancer.
Barbieri I, Kouzarides T. Barbieri I, et al. Nat Rev Cancer. 2020 Jun;20(6):303-322. doi: 10.1038/s41568-020-0253-2. Epub 2020 Apr 16. Nat Rev Cancer. 2020. PMID: 32300195 Review.
A versatile drug delivery system targeting senescent cells.
Muñoz-Espín D, Rovira M, Galiana I, Giménez C, Lozano-Torres B, Paez-Ribes M, Llanos S, Chaib S, Muñoz-Martín M, Ucero AC, Garaulet G, Mulero F, Dann SG, VanArsdale T, Shields DJ, Bernardos A, Murguía JR, Martínez-Máñez R, Serrano M. Muñoz-Espín D, et al. EMBO Mol Med. 2018 Sep;10(9):e9355. doi: 10.15252/emmm.201809355. EMBO Mol Med. 2018. PMID: 30012580 Free PMC article.