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Non-thermal disruption of β-adrenergic receptor-activated Ca2+ signalling and apoptosis in human ES-derived cardiomyocytes by microwave electric fields at 2.4 GHz.
Williams CF, Hather C, Conteh JS, Zhang J, Popa RG, Owen AW, Jonas CL, Choi H, Daniel RM, Lloyd D, Porch A, George CH. Williams CF, et al. Biochem Biophys Res Commun. 2023 Jun 18;661:89-98. doi: 10.1016/j.bbrc.2023.04.038. Epub 2023 Apr 17. Biochem Biophys Res Commun. 2023. PMID: 37087803 Free article.
Ero1α-Dependent ERp44 Dissociation From RyR2 Contributes to Cardiac Arrhythmia.
Hamilton S, Terentyeva R, Bogdanov V, Kim TY, Perger F, Yan J, Ai X, Carnes CA, Belevych AE, George CH, Davis JP, Gyorke S, Choi BR, Terentyev D. Hamilton S, et al. Circ Res. 2022 Mar 4;130(5):711-724. doi: 10.1161/CIRCRESAHA.121.320531. Epub 2022 Jan 28. Circ Res. 2022. PMID: 35086342 Free PMC article.
Increased tissue stiffness triggers contractile dysfunction and telomere shortening in dystrophic cardiomyocytes.
Chang ACY, Pardon G, Chang ACH, Wu H, Ong SG, Eguchi A, Ancel S, Holbrook C, Ramunas J, Ribeiro AJS, LaGory EL, Wang H, Koleckar K, Giaccia A, Mack DL, Childers MK, Denning C, Day JW, Wu JC, Pruitt BL, Blau HM. Chang ACY, et al. Stem Cell Reports. 2021 Sep 14;16(9):2169-2181. doi: 10.1016/j.stemcr.2021.04.018. Epub 2021 May 20. Stem Cell Reports. 2021. PMID: 34019816 Free PMC article.
Blinded, Multicenter Evaluation of Drug-induced Changes in Contractility Using Human-induced Pluripotent Stem Cell-derived Cardiomyocytes.
Saleem U, van Meer BJ, Katili PA, Mohd Yusof NAN, Mannhardt I, Garcia AK, Tertoolen L, de Korte T, Vlaming MLH, McGlynn K, Nebel J, Bahinski A, Harris K, Rossman E, Xu X, Burton FL, Smith GL, Clements P, Mummery CL, Eschenhagen T, Hansen A, Denning C. Saleem U, et al. Toxicol Sci. 2020 Jul 1;176(1):103-123. doi: 10.1093/toxsci/kfaa058. Toxicol Sci. 2020. PMID: 32421822 Free PMC article.
Unlocking Personalized Biomedicine and Drug Discovery with Human Induced Pluripotent Stem Cell-Derived Cardiomyocytes: Fit for Purpose or Forever Elusive?
de Korte T, Katili PA, Mohd Yusof NAN, van Meer BJ, Saleem U, Burton FL, Smith GL, Clements P, Mummery CL, Eschenhagen T, Hansen A, Denning C. de Korte T, et al. Annu Rev Pharmacol Toxicol. 2020 Jan 6;60:529-551. doi: 10.1146/annurev-pharmtox-010919-023309. Epub 2019 Sep 10. Annu Rev Pharmacol Toxicol. 2020. PMID: 31506008 Review.
Polymer Microparticles with Defined Surface Chemistry and Topography Mediate the Formation of Stem Cell Aggregates and Cardiomyocyte Function.
Alvarez-Paino M, Amer MH, Nasir A, Cuzzucoli Crucitti V, Thorpe J, Burroughs L, Needham D, Denning C, Alexander MR, Alexander C, Rose FRAJ. Alvarez-Paino M, et al. ACS Appl Mater Interfaces. 2019 Sep 25;11(38):34560-34574. doi: 10.1021/acsami.9b04769. Epub 2019 Sep 10. ACS Appl Mater Interfaces. 2019. PMID: 31502820
19 results