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Targeted and selective knockout of the TLQP-21 neuropeptide unmasks its unique role in energy homeostasis.
Sahu BS, Razzoli M, McGonigle S, Pallais JP, Nguyen ME, Sadahiro M, Jiang C, Lin WJ, Kelley KA, Rodriguez P, Mansk R, Cero C, Caviola G, Palanza P, Rao L, Beetch M, Alejandro E, Sham YY, Frontini A, Salton SR, Bartolomucci A. Sahu BS, et al. Mol Metab. 2023 Oct;76:101781. doi: 10.1016/j.molmet.2023.101781. Epub 2023 Jul 21. Mol Metab. 2023. PMID: 37482186 Free PMC article.
The molecular identity of the TLQP-21 peptide receptor.
Sahu BS, Nguyen ME, Rodriguez P, Pallais JP, Ghosh V, Razzoli M, Sham YY, Salton SR, Bartolomucci A. Sahu BS, et al. Cell Mol Life Sci. 2021 Dec;78(23):7133-7144. doi: 10.1007/s00018-021-03944-1. Epub 2021 Oct 9. Cell Mol Life Sci. 2021. PMID: 34626205 Free PMC article. Review.
Multiscale causal networks identify VGF as a key regulator of Alzheimer's disease.
Beckmann ND, Lin WJ, Wang M, Cohain AT, Charney AW, Wang P, Ma W, Wang YC, Jiang C, Audrain M, Comella PH, Fakira AK, Hariharan SP, Belbin GM, Girdhar K, Levey AI, Seyfried NT, Dammer EB, Duong D, Lah JJ, Haure-Mirande JV, Shackleton B, Fanutza T, Blitzer R, Kenny E, Zhu J, Haroutunian V, Katsel P, Gandy S, Tu Z, Ehrlich ME, Zhang B, Salton SR, Schadt EE. Beckmann ND, et al. Nat Commun. 2020 Aug 7;11(1):3942. doi: 10.1038/s41467-020-17405-z. Nat Commun. 2020. PMID: 32770063 Free PMC article.