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Restricted fluid resuscitation in suspected sepsis associated hypotension (REFRESH): a pilot randomised controlled trial.
Macdonald SPJ, Keijzers G, Taylor DM, Kinnear F, Arendts G, Fatovich DM, Bellomo R, McCutcheon D, Fraser JF, Ascencio-Lane JC, Burrows S, Litton E, Harley A, Anstey M, Mukherjee A; REFRESH trial investigators. Macdonald SPJ, et al. Intensive Care Med. 2018 Dec;44(12):2070-2078. doi: 10.1007/s00134-018-5433-0. Epub 2018 Oct 31. Intensive Care Med. 2018. PMID: 30382308 Clinical Trial.
Effect of intravenous fluid volume on biomarkers of endothelial glycocalyx shedding and inflammation during initial resuscitation of sepsis.
Macdonald S, Bosio E, Keijzers G, Burrows S, Hibbs M, O'Donoghue H, Taylor D, Mukherjee A, Kinnear F, Smart L, Ascencio-Lane JC, Litton E, Fraser J, Shapiro NI, Arendts G, Fatovich D; REFRESH Trial Investigators. Macdonald S, et al. Intensive Care Med Exp. 2023 Apr 17;11(1):21. doi: 10.1186/s40635-023-00508-4. Intensive Care Med Exp. 2023. PMID: 37062769 Free PMC article.