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Microbiota-derived metabolite promotes HDAC3 activity in the gut.
Wu SE, Hashimoto-Hill S, Woo V, Eshleman EM, Whitt J, Engleman L, Karns R, Denson LA, Haslam DB, Alenghat T. Wu SE, et al. Nature. 2020 Oct;586(7827):108-112. doi: 10.1038/s41586-020-2604-2. Epub 2020 Jul 30. Nature. 2020. PMID: 32731255 Free PMC article.
Microbiota-sensitive epigenetic signature predicts inflammation in Crohn's disease.
Kelly D, Kotliar M, Woo V, Jagannathan S, Whitt J, Moncivaiz J, Aronow BJ, Dubinsky MC, Hyams JS, Markowitz JF, Baldassano RN, Stephens MC, Walters TD, Kugathasan S, Haberman Y, Sundaram N, Rosen MJ, Helmrath M, Karns R, Barski A, Denson LA, Alenghat T. Kelly D, et al. JCI Insight. 2018 Sep 20;3(18):e122104. doi: 10.1172/jci.insight.122104. eCollection 2018 Sep 20. JCI Insight. 2018. PMID: 30232290 Free PMC article.