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eQTL studies: from bulk tissues to single cells.
Zhang J, Zhao H. Zhang J, et al. J Genet Genomics. 2023 Dec;50(12):925-933. doi: 10.1016/j.jgg.2023.05.003. Epub 2023 May 18. J Genet Genomics. 2023. PMID: 37207929 Free article. Review.
Single-cell transcriptomic atlas of Alzheimer's disease middle temporal gyrus reveals region, cell type and sex specificity of gene expression with novel genetic risk for MERTK in female.
Zhang L, He CH, Coffey S, Yin D, Hsu IU, Su C, Ye Y, Zhang C, Spurrier J, Nicholson L, Rothlin CV, Ghosh S, Gopal PP, Hafler DA, Zhao H, Strittmatter SM. Zhang L, et al. medRxiv [Preprint]. 2023 Feb 23:2023.02.18.23286037. doi: 10.1101/2023.02.18.23286037. medRxiv. 2023. PMID: 36865305 Free PMC article. Preprint.
Reversal of synapse loss in Alzheimer mouse models by targeting mGluR5 to prevent synaptic tagging by C1Q.
Spurrier J, Nicholson L, Fang XT, Stoner AJ, Toyonaga T, Holden D, Siegert TR, Laird W, Allnutt MA, Chiasseu M, Brody AH, Takahashi H, Nies SH, Pérez-Cañamás A, Sadasivam P, Lee S, Li S, Zhang L, Huang YH, Carson RE, Cai Z, Strittmatter SM. Spurrier J, et al. Sci Transl Med. 2022 Jun;14(647):eabi8593. doi: 10.1126/scitranslmed.abi8593. Epub 2022 Jun 1. Sci Transl Med. 2022. PMID: 35648810 Free PMC article.
12 results