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2017 2
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Page 1
Synthesis and SAR of a novel Kir6.2/SUR1 channel opener scaffold identified by HTS.
Dodd CJ, Chronister KS, Rathnayake U, Parr LC, Li K, Chang S, Mi D, Days EL, Bauer JA, Cho HP, Boutaud O, Denton JS, Lindsley CW, Han C. Dodd CJ, et al. Bioorg Med Chem Lett. 2023 May 1;87:129256. doi: 10.1016/j.bmcl.2023.129256. Epub 2023 Mar 24. Bioorg Med Chem Lett. 2023. PMID: 36966977 Free PMC article.
A selective inhibitor of the sperm-specific potassium channel SLO3 impairs human sperm function.
Lyon M, Li P, Ferreira JJ, Lazarenko RM, Kharade SV, Kramer M, McClenahan SJ, Days E, Bauer JA, Spitznagel BD, Weaver CD, Borrego Alvarez A, Puga Molina LC, Lybaert P, Khambekar S, Liu A, Lindsley CW, Denton J, Santi CM. Lyon M, et al. Proc Natl Acad Sci U S A. 2023 Jan 24;120(4):e2212338120. doi: 10.1073/pnas.2212338120. Epub 2023 Jan 17. Proc Natl Acad Sci U S A. 2023. PMID: 36649421 Free PMC article.
VU6036720: The First Potent and Selective In Vitro Inhibitor of Heteromeric Kir4.1/5.1 Inward Rectifier Potassium Channels.
McClenahan SJ, Kent CN, Kharade SV, Isaeva E, Williams JC, Han C, Terker A, Gresham R 3rd, Lazarenko RM, Days EL, Romaine IM, Bauer JA, Boutaud O, Sulikowski GA, Harris R, Weaver CD, Staruschenko A, Lindsley CW, Denton JS. McClenahan SJ, et al. Mol Pharmacol. 2022 May;101(5):357-370. doi: 10.1124/molpharm.121.000464. Epub 2022 Mar 3. Mol Pharmacol. 2022. PMID: 35246480 Free PMC article.
22 results