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Year | Number of Results |
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2011 | 1 |
2018 | 1 |
2019 | 1 |
2020 | 2 |
2024 | 0 |
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Page 1
Garcinoic Acid Is a Natural and Selective Agonist of Pregnane X Receptor.
J Med Chem. 2020 Apr 9;63(7):3701-3712. doi: 10.1021/acs.jmedchem.0c00012. Epub 2020 Mar 20.
J Med Chem. 2020.
PMID: 32160459
Free PMC article.
Targeting the pregnane X receptor using microbial metabolite mimicry.
Dvořák Z, Kopp F, Costello CM, Kemp JS, Li H, Vrzalová A, Štěpánková M, Bartoňková I, Jiskrová E, Poulíková K, Vyhlídalová B, Nordstroem LU, Karunaratne CV, Ranhotra HS, Mun KS, Naren AP, Murray IA, Perdew GH, Brtko J, Toporova L, Schön A, Wallace BD, Walton WG, Redinbo MR, Sun K, Beck A, Kortagere S, Neary MC, Chandran A, Vishveshwara S, Cavalluzzi MM, Lentini G, Cui JY, Gu H, March JC, Chatterjee S, Matson A, Wright D, Flannigan KL, Hirota SA, Sartor RB, Mani S.
Dvořák Z, et al.
EMBO Mol Med. 2020 Apr 7;12(4):e11621. doi: 10.15252/emmm.201911621. Epub 2020 Mar 10.
EMBO Mol Med. 2020.
PMID: 32153125
Free PMC article.
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Mono-methylindoles induce CYP1A genes and inhibit CYP1A1 enzyme activity in human hepatocytes and HepaRG cells.
Vyhlídalová B, Poulíková K, Bartoňková I, Krasulová K, Vančo J, Trávníček Z, Mani S, Dvořák Z.
Vyhlídalová B, et al.
Toxicol Lett. 2019 Oct 1;313:66-76. doi: 10.1016/j.toxlet.2019.06.004. Epub 2019 Jun 12.
Toxicol Lett. 2019.
PMID: 31201936
Free PMC article.
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Methylindoles and Methoxyindoles are Agonists and Antagonists of Human Aryl Hydrocarbon Receptor.
Stepankova M, Bartonkova I, Jiskrova E, Vrzal R, Mani S, Kortagere S, Dvorak Z.
Stepankova M, et al.
Mol Pharmacol. 2018 Jun;93(6):631-644. doi: 10.1124/mol.118.112151. Epub 2018 Apr 6.
Mol Pharmacol. 2018.
PMID: 29626056
Free PMC article.
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In vivo and in vitro characterization of a first-in-class novel azole analog that targets pregnane X receptor activation.
Venkatesh M, Wang H, Cayer J, Leroux M, Salvail D, Das B, Wrobel JE, Mani S.
Venkatesh M, et al.
Mol Pharmacol. 2011 Jul;80(1):124-35. doi: 10.1124/mol.111.071787. Epub 2011 Apr 4.
Mol Pharmacol. 2011.
PMID: 21464197
Free PMC article.
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