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miR-661 downregulates both Mdm2 and Mdm4 to activate p53.
Hoffman Y, Bublik DR, Pilpel Y, Oren M. Hoffman Y, et al. Cell Death Differ. 2014 Feb;21(2):302-9. doi: 10.1038/cdd.2013.146. Epub 2013 Oct 18. Cell Death Differ. 2014. PMID: 24141721 Free PMC article.
p53: guardian of ploidy.
Aylon Y, Oren M. Aylon Y, et al. Mol Oncol. 2011 Aug;5(4):315-23. doi: 10.1016/j.molonc.2011.07.007. Epub 2011 Jul 30. Mol Oncol. 2011. PMID: 21852209 Free PMC article. Review.
Requirement of ATM-dependent monoubiquitylation of histone H2B for timely repair of DNA double-strand breaks.
Moyal L, Lerenthal Y, Gana-Weisz M, Mass G, So S, Wang SY, Eppink B, Chung YM, Shalev G, Shema E, Shkedy D, Smorodinsky NI, van Vliet N, Kuster B, Mann M, Ciechanover A, Dahm-Daphi J, Kanaar R, Hu MC, Chen DJ, Oren M, Shiloh Y. Moyal L, et al. Mol Cell. 2011 Mar 4;41(5):529-42. doi: 10.1016/j.molcel.2011.02.015. Mol Cell. 2011. PMID: 21362549 Free PMC article.
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