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Table representation of search results timeline featuring number of search results per year.

Year Number of Results
2007 1
2010 1
2011 2
2012 5
2013 2
2014 3
2015 14
2016 16
2017 15
2018 11
2019 16
2020 14
2021 31
2022 18
2023 17
2024 6

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151 results

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Page 1
Evaluation of Exploratory Fluid Biomarker Results from a Phase 1 Senolytic Trial in Mild Alzheimer's Disease.
Garbarino VR, Palavicini JP, Melendez J, Barthelemy N, He Y, Kautz TF, Lopez-Cruzan M, Mathews JJ, Xu P, Zhan B, Saliba A, Ragi N, Sharma K, Craft S, Petersen RC, Espindola-Netto JM, Xue A, Tchkonia T, Kirkland JL, Seshadri S, Salardini A, Musi N, Bateman RJ, Gonzales MM, Orr ME. Garbarino VR, et al. Res Sq [Preprint]. 2024 Mar 8:rs.3.rs-3994894. doi: 10.21203/rs.3.rs-3994894/v1. Res Sq. 2024. PMID: 38496619 Free PMC article. Preprint.
The efficacy of chemotherapy is limited by intratumoral senescent cells expressing PD-L2.
Chaib S, López-Domínguez JA, Lalinde-Gutiérrez M, Prats N, Marin I, Boix O, García-Garijo A, Meyer K, Muñoz MI, Aguilera M, Mateo L, Stephan-Otto Attolini C, Llanos S, Pérez-Ramos S, Escorihuela M, Al-Shahrour F, Cash TP, Tchkonia T, Kirkland JL, Abad M, Gros A, Arribas J, Serrano M. Chaib S, et al. Nat Cancer. 2024 Mar;5(3):448-462. doi: 10.1038/s43018-023-00712-x. Epub 2024 Jan 24. Nat Cancer. 2024. PMID: 38267628 Free PMC article.
An untapped window of opportunity for glioma: targeting therapy-induced senescence prior to recurrence.
Riviere-Cazaux C, Carlstrom LP, Neth BJ, Olson IE, Rajani K, Rahman M, Ikram S, Mansour MA, Mukherjee B, Warrington AE, Short SC, von Zglinicki T, Brown DA, Burma S, Tchkonia T, Schafer MJ, Baker DJ, Kizilbash SH, Kirkland JL, Burns TC. Riviere-Cazaux C, et al. NPJ Precis Oncol. 2023 Nov 29;7(1):126. doi: 10.1038/s41698-023-00476-8. NPJ Precis Oncol. 2023. PMID: 38030881 Free PMC article. Review.
Transplanting old organs promotes senescence in young recipients.
Iske J, Roesel MJ, Martin F, Schroeter A, Matsunaga T, Maenosono R, Tripathi U, Xiao Y, Nian Y, Caldarone BJ, Vondran FWR, Sage PT, Azuma H, Abdi R, Elkhal A, Pirtskhalava T, Tchkonia T, Kirkland JL, Zhou H, Tullius SG. Iske J, et al. Am J Transplant. 2024 Mar;24(3):391-405. doi: 10.1016/j.ajt.2023.10.013. Epub 2023 Oct 31. Am J Transplant. 2024. PMID: 37913871
Senolytic therapy in mild Alzheimer's disease: a phase 1 feasibility trial.
Gonzales MM, Garbarino VR, Kautz TF, Palavicini JP, Lopez-Cruzan M, Dehkordi SK, Mathews JJ, Zare H, Xu P, Zhang B, Franklin C, Habes M, Craft S, Petersen RC, Tchkonia T, Kirkland JL, Salardini A, Seshadri S, Musi N, Orr ME. Gonzales MM, et al. Nat Med. 2023 Oct;29(10):2481-2488. doi: 10.1038/s41591-023-02543-w. Epub 2023 Sep 7. Nat Med. 2023. PMID: 37679434 Free PMC article. Clinical Trial.
Challenges in developing Geroscience trials.
Rolland Y, Sierra F, Ferrucci L, Barzilai N, De Cabo R, Mannick J, Oliva A, Evans W, Angioni D, De Souto Barreto P, Raffin J, Vellas B, Kirkland JL; G.C.T-TF group. Rolland Y, et al. Nat Commun. 2023 Aug 19;14(1):5038. doi: 10.1038/s41467-023-39786-7. Nat Commun. 2023. PMID: 37598227 Free PMC article. Review.
Interleukin-6 in Patients With Heart Failure and Preserved Ejection Fraction.
Alogna A, Koepp KE, Sabbah M, Espindola Netto JM, Jensen MD, Kirkland JL, Lam CSP, Obokata M, Petrie MC, Ridker PM, Sorimachi H, Tchkonia T, Voors A, Redfield MM, Borlaug BA. Alogna A, et al. JACC Heart Fail. 2023 Nov;11(11):1549-1561. doi: 10.1016/j.jchf.2023.06.031. Epub 2023 Aug 9. JACC Heart Fail. 2023. PMID: 37565977 Free PMC article.
151 results