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Aortic Stress Activates an Adaptive Program in Thoracic Aortic Smooth Muscle Cells That Maintains Aortic Strength and Protects Against Aneurysm and Dissection in Mice.
Zhang C, Li Y, Chakraborty A, Li Y, Rebello KR, Ren P, Luo W, Zhang L, Lu HS, Cassis LA, Coselli JS, Daugherty A, LeMaire SA, Shen YH. Zhang C, et al. Arterioscler Thromb Vasc Biol. 2023 Feb;43(2):234-252. doi: 10.1161/ATVBAHA.122.318135. Epub 2022 Dec 29. Arterioscler Thromb Vasc Biol. 2023. PMID: 36579645 Free PMC article.
LRP1 protects against excessive superior mesenteric artery remodeling by modulating angiotensin II-mediated signaling.
Zhang JM, Au DT, Sawada H, Franklin MK, Moorleghen JJ, Howatt DA, Wang P, Aicher BO, Hampton B, Migliorini M, Ni F, Mullick AE, Wani MM, Ucuzian AA, Lu HS, Muratoglu SC, Daugherty A, Strickland DK. Zhang JM, et al. JCI Insight. 2023 Jan 24;8(2):e164751. doi: 10.1172/jci.insight.164751. JCI Insight. 2023. PMID: 36472907 Free PMC article.
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