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2021 4
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Mediator Kinase Inhibition Impedes Transcriptional Plasticity and Prevents Resistance to ERK/MAPK-Targeted Therapy in KRAS-Mutant Cancers.
Wood K, Nussbaum D, Martz C, Waters A, Barrera A, Rutter J, Cerda-Smith C, Stewart A, Wu C, Cakir M, Levandowski C, Kantrowitz D, McCall S, Pierobon M, Petricoin E 3rd, Smith J, Der C, Taatjes D. Wood K, et al. Res Sq [Preprint]. 2023 Nov 2:rs.3.rs-3511242. doi: 10.21203/rs.3.rs-3511242/v1. Res Sq. 2023. PMID: 37961649 Free PMC article. Preprint.
An atlas of substrate specificities for the human serine/threonine kinome.
Johnson JL, Yaron TM, Huntsman EM, Kerelsky A, Song J, Regev A, Lin TY, Liberatore K, Cizin DM, Cohen BM, Vasan N, Ma Y, Krismer K, Robles JT, van de Kooij B, van Vlimmeren AE, Andrée-Busch N, Käufer NF, Dorovkov MV, Ryazanov AG, Takagi Y, Kastenhuber ER, Goncalves MD, Hopkins BD, Elemento O, Taatjes DJ, Maucuer A, Yamashita A, Degterev A, Uduman M, Lu J, Landry SD, Zhang B, Cossentino I, Linding R, Blenis J, Hornbeck PV, Turk BE, Yaffe MB, Cantley LC. Johnson JL, et al. Nature. 2023 Jan;613(7945):759-766. doi: 10.1038/s41586-022-05575-3. Epub 2023 Jan 11. Nature. 2023. PMID: 36631611 Free PMC article.
SnapShot: Mediator complex structure.
Nayak S, Taatjes DJ. Nayak S, et al. Cell. 2022 Sep 1;185(18):3458-3458.e1. doi: 10.1016/j.cell.2022.07.011. Cell. 2022. PMID: 36055203 Free PMC article.
Chemical inhibitors of transcription-associated kinases.
Clopper KC, Taatjes DJ. Clopper KC, et al. Curr Opin Chem Biol. 2022 Oct;70:102186. doi: 10.1016/j.cbpa.2022.102186. Epub 2022 Aug 1. Curr Opin Chem Biol. 2022. PMID: 35926294 Free PMC article. Review.
14 results