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Page 1
Catalytic site mutations confer multiple states of G protein activation.
Hewitt N, Ma N, Arang N, Martin SA, Prakash A, DiBerto JF, Knight KM, Ghosh S, Olsen RHJ, Roth BL, Gutkind JS, Vaidehi N, Campbell SL, Dohlman HG. Hewitt N, et al. Sci Signal. 2023 Feb 14;16(772):eabq7842. doi: 10.1126/scisignal.abq7842. Epub 2023 Feb 14. Sci Signal. 2023. PMID: 36787384 Free PMC article.
Functional and biological heterogeneity of KRASQ61 mutations.
Huynh MV, Hobbs GA, Schaefer A, Pierobon M, Carey LM, Diehl JN, DeLiberty JM, Thurman RD, Cooke AR, Goodwin CM, Cook JH, Lin L, Waters AM, Rashid NU, Petricoin EF 3rd, Campbell SL, Haigis KM, Simeone DM, Lyssiotis CA, Cox AD, Der CJ. Huynh MV, et al. Sci Signal. 2022 Aug 9;15(746):eabn2694. doi: 10.1126/scisignal.abn2694. Epub 2022 Aug 9. Sci Signal. 2022. PMID: 35944066 Free PMC article.
Post-translational modification of RAS proteins.
Campbell SL, Philips MR. Campbell SL, et al. Curr Opin Struct Biol. 2021 Dec;71:180-192. doi: 10.1016/j.sbi.2021.06.015. Epub 2021 Aug 6. Curr Opin Struct Biol. 2021. PMID: 34365229 Free PMC article. Review.
A universal allosteric mechanism for G protein activation.
Knight KM, Ghosh S, Campbell SL, Lefevre TJ, Olsen RHJ, Smrcka AV, Valentin NH, Yin G, Vaidehi N, Dohlman HG. Knight KM, et al. Mol Cell. 2021 Apr 1;81(7):1384-1396.e6. doi: 10.1016/j.molcel.2021.02.002. Epub 2021 Feb 25. Mol Cell. 2021. PMID: 33636126 Free PMC article.
20 results