R35 GM131812/GM/NIGMS NIH HHS/United States[Grants and Funding] - Search Results

Year	Number of Results
2018	1
2019	7
2020	5
2021	4
2022	3
2023	3
2024	1

1

Functional Analysis of G6PD Variants Associated With Low G6PD Activity in the All of Us Research Program.

Powell NR, Geck RC, Lai D, Shugg T, Skaar TC, Dunham M. Powell NR, et al. medRxiv [Preprint]. 2024 Apr 14:2024.04.12.24305393. doi: 10.1101/2024.04.12.24305393. medRxiv. 2024. PMID: 38645242 Free PMC article. Preprint.

2

The INGENIOUS trial: Impact of pharmacogenetic testing on adverse events in a pragmatic clinical trial.

Eadon MT, Rosenman MB, Zhang P, Fulton CR, Callaghan JT, Holmes AM, Levy KD, Gupta SK, Haas DM, Vuppalanchi R, Benson EA, Kreutz RP, Tillman EM, Shugg T, Pierson RC, Gufford BT, Pratt VM, Zang Y, Desta Z, Dexter PR, Skaar TC. Eadon MT, et al. Pharmacogenomics J. 2023 Nov;23(6):169-177. doi: 10.1038/s41397-023-00315-w. Epub 2023 Sep 9. Pharmacogenomics J. 2023. PMID: 37689822 Clinical Trial.

3

Analysis of the Combined Effect of rs699 and rs5051 on Angiotensinogen Expression and Hypertension.

Powell NR, Shugg T, Leighty J, Martin M, Kreutz RP, Eadon MT, Lai D, Lu T, Skaar TC. Powell NR, et al. bioRxiv [Preprint]. 2023 Apr 8:2023.04.07.536073. doi: 10.1101/2023.04.07.536073. bioRxiv. 2023. PMID: 37066278 Free PMC article. Preprint.

4

Clinically important alterations in pharmacogene expression in histologically severe nonalcoholic fatty liver disease.

Powell NR, Liang T, Ipe J, Cao S, Skaar TC, Desta Z, Qian HR, Ebert PJ, Chen Y, Thomas MK, Chalasani N. Powell NR, et al. Nat Commun. 2023 Mar 17;14(1):1474. doi: 10.1038/s41467-023-37209-1. Nat Commun. 2023. PMID: 36927865 Free PMC article.

5

Analytical Validation of a Computational Method for Pharmacogenetic Genotyping from Clinical Whole Exome Sequencing.

Ly RC, Shugg T, Ratcliff R, Osei W, Lynnes TC, Pratt VM, Schneider BP, Radovich M, Bray SM, Salisbury BA, Parikh B, Sahinalp SC, Numanagić I, Skaar TC. Ly RC, et al. J Mol Diagn. 2022 Jun;24(6):576-585. doi: 10.1016/j.jmoldx.2022.03.008. Epub 2022 Apr 20. J Mol Diagn. 2022. PMID: 35452844 Free PMC article.

6

Clinical Opportunities for Germline Pharmacogenetics and Management of Drug-Drug Interactions in Patients With Advanced Solid Cancers.

Shugg T, Ly RC, Rowe EJ, Philips S, Hyder MA, Radovich M, Rosenman MB, Pratt VM, Callaghan JT, Desta Z, Schneider BP, Skaar TC. Shugg T, et al. JCO Precis Oncol. 2022 Feb;6:e2100312. doi: 10.1200/PO.21.00312. JCO Precis Oncol. 2022. PMID: 35201852 Free PMC article.

7

Life-Threatening Docetaxel Toxicity in a Patient With Reduced-Function CYP3A Variants: A Case Report.

Powell NR, Shugg T, Ly RC, Albany C, Radovich M, Schneider BP, Skaar TC. Powell NR, et al. Front Oncol. 2022 Jan 31;11:809527. doi: 10.3389/fonc.2021.809527. eCollection 2021. Front Oncol. 2022. PMID: 35174070 Free PMC article.

8

Mapping the miRNA-mRNA Interactome in Human Hepatocytes and Identification of Functional mirSNPs in Pharmacogenes.

Powell NR, Zhao H, Ipe J, Liu Y, Skaar TC. Powell NR, et al. Clin Pharmacol Ther. 2021 Oct;110(4):1106-1118. doi: 10.1002/cpt.2379. Epub 2021 Aug 13. Clin Pharmacol Ther. 2021. PMID: 34314509 Free PMC article.

9

Severe Capecitabine Toxicity Associated With a Rare DPYD Variant Identified Through Whole-Genome Sequencing.

Ly RC, Schmidt RE, Kiel PJ, Pratt VM, Schneider BP, Radovich M, Offer SM, Diasio RB, Skaar TC. Ly RC, et al. JCO Precis Oncol. 2020 Jun 12;4:PO.20.00067. doi: 10.1200/PO.20.00067. eCollection 2020. JCO Precis Oncol. 2020. PMID: 32923881 Free PMC article. No abstract available.

10

Circulating miRNAs as Biomarkers for CYP2B6 Enzyme Activity.

Ipe J, Li R, Metzger IF, Bo Li Lu J, Gufford BT, Desta Z, Liu Y, Skaar TC. Ipe J, et al. Clin Pharmacol Ther. 2021 Feb;109(2):485-493. doi: 10.1002/cpt.2018. Epub 2020 Oct 5. Clin Pharmacol Ther. 2021. PMID: 32772362 Free PMC article.

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