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2017 1
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2020 7
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2023 5
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Page 1
RALDH1 Inhibition Shows Immunotherapeutic Efficacy in Hepatocellular Carcinoma.
Yu P, Cao S, Yang SM, Rai G, Martinez NJ, Yasgar A, Zakharov AV, Simeonov A, Molina Arocho WA, Lobel GP, Mohei H, Scott AL, Zhai L, Furth EE, Simon MC, Haldar M. Yu P, et al. Cancer Immunol Res. 2024 Feb 2;12(2):180-194. doi: 10.1158/2326-6066.CIR-22-1023. Cancer Immunol Res. 2024. PMID: 38051215
Disrupting cellular memory to overcome drug resistance.
Harmange G, Hueros RAR, Schaff DL, Emert B, Saint-Antoine M, Kim LC, Niu Z, Nellore S, Fane ME, Alicea GM, Weeraratna AT, Simon MC, Singh A, Shaffer SM. Harmange G, et al. Nat Commun. 2023 Nov 6;14(1):7130. doi: 10.1038/s41467-023-41811-8. Nat Commun. 2023. PMID: 37932277 Free PMC article.
Fructose-1,6-bisphosphatase is a nonenzymatic safety valve that curtails AKT activation to prevent insulin hyperresponsiveness.
Gu L, Zhu Y, Watari K, Lee M, Liu J, Perez S, Thai M, Mayfield JE, Zhang B, Cunha E Rocha K, Li F, Kim LC, Jones AC, Wierzbicki IH, Liu X, Newton AC, Kisseleva T, Lee JH, Ying W, Gonzalez DJ, Saltiel AR, Simon MC, Karin M. Gu L, et al. Cell Metab. 2023 Jun 6;35(6):1009-1021.e9. doi: 10.1016/j.cmet.2023.03.021. Epub 2023 Apr 20. Cell Metab. 2023. PMID: 37084733 Free PMC article.
Activation of γ-globin expression by hypoxia-inducible factor 1α.
Feng R, Mayuranathan T, Huang P, Doerfler PA, Li Y, Yao Y, Zhang J, Palmer LE, Mayberry K, Christakopoulos GE, Xu P, Li C, Cheng Y, Blobel GA, Simon MC, Weiss MJ. Feng R, et al. Nature. 2022 Oct;610(7933):783-790. doi: 10.1038/s41586-022-05312-w. Epub 2022 Oct 12. Nature. 2022. PMID: 36224385 Free PMC article.
39 results