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Chronic immune activation and gut barrier dysfunction is associated with neuroinflammation in ART-suppressed SIV+ rhesus macaques.
Byrnes SJ, Busman-Sahay K, Angelovich TA, Younger S, Taylor-Brill S, Nekorchuk M, Bondoc S, Dannay R, Terry M, Cochrane CR, Jenkins TA, Roche M, Deleage C, Bosinger SE, Paiardini M, Brew BJ, Estes JD, Churchill MJ. Byrnes SJ, et al. PLoS Pathog. 2023 Mar 29;19(3):e1011290. doi: 10.1371/journal.ppat.1011290. eCollection 2023 Mar. PLoS Pathog. 2023. PMID: 36989320 Free PMC article.
Tissue-specific transcriptional profiling of plasmacytoid dendritic cells reveals a hyperactivated state in chronic SIV infection.
Lee MY, Upadhyay AA, Walum H, Chan CN, Dawoud RA, Grech C, Harper JL, Karunakaran KA, Nelson SA, Mahar EA, Goss KL, Carnathan DG, Cervasi B, Gill K, Tharp GK, Wonderlich ER, Velu V, Barratt-Boyes SM, Paiardini M, Silvestri G, Estes JD, Bosinger SE. Lee MY, et al. PLoS Pathog. 2021 Jun 28;17(6):e1009674. doi: 10.1371/journal.ppat.1009674. eCollection 2021 Jun. PLoS Pathog. 2021. PMID: 34181694 Free PMC article.
Macrophage-associated wound healing contributes to African green monkey SIV pathogenesis control.
Barrenas F, Raehtz K, Xu C, Law L, Green RR, Silvestri G, Bosinger SE, Nishida A, Li Q, Lu W, Zhang J, Thomas MJ, Chang J, Smith E, Weiss JM, Dawoud RA, Richter GH, Trichel A, Ma D, Peng X, Komorowski J, Apetrei C, Pandrea I, Gale M Jr. Barrenas F, et al. Nat Commun. 2019 Nov 8;10(1):5101. doi: 10.1038/s41467-019-12987-9. Nat Commun. 2019. PMID: 31704931 Free PMC article.
Sooty mangabey genome sequence provides insight into AIDS resistance in a natural SIV host.
Palesch D, Bosinger SE, Tharp GK, Vanderford TH, Paiardini M, Chahroudi A, Johnson ZP, Kirchhoff F, Hahn BH, Norgren RB, Patel NB, Sodora DL, Dawoud RA, Stewart CB, Seepo SM, Harris RA, Liu Y, Raveendran M, Han Y, English A, Thomas GWC, Hahn MW, Pipes L, Mason CE, Muzny DM, Gibbs RA, Sauter D, Worley K, Rogers J, Silvestri G. Palesch D, et al. Nature. 2018 Jan 3;553(7686):77-81. doi: 10.1038/nature25140. Nature. 2018. PMID: 29300007 Free PMC article.