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Netrin-1 feedforward mechanism promotes pancreatic cancer liver metastasis via hepatic stellate cell activation, retinoid, and ELF3 signaling.
Dudgeon C, Casabianca A, Harris C, Ogier C, Bellina M, Fiore S, Bernet A, Ducarouge B, Goldschneider D, Su X, Pitarresi J, Hezel A, De S, Narrow W, Soliman F, Shields C, Vendramini-Costa DB, Prela O, Wang L, Astsaturov I, Mehlen P, Carpizo DR. Dudgeon C, et al. Cell Rep. 2023 Nov 28;42(11):113369. doi: 10.1016/j.celrep.2023.113369. Epub 2023 Nov 3. Cell Rep. 2023. PMID: 37922311 Free article.
Trogocytosis of cancer-associated fibroblasts promotes pancreatic cancer growth and immune suppression via phospholipid scramblase anoctamin 6 (ANO6).
Ogier C, Solomon AMC, Lu Z, Recoules L, Klochkova A, Gabitova-Cornell L, Bayarmagnai B, Restifo D, Surumbayeva A, Vendramini-Costa DB, Deneka AY, Francescone R, Lilly AC, Sipman A, Gardiner JC, Luong T, Franco-Barraza J, Ibeme N, Cai KQ, Einarson MB, Nicolas E, Efimov A, Megill E, Snyder NW, Bousquet C, Cros J, Zhou Y, Golemis EA, Gligorijevic B, Soboloff J, Fuchs SY, Cukierman E, Astsaturov I. Ogier C, et al. bioRxiv [Preprint]. 2023 Sep 17:2023.09.15.557802. doi: 10.1101/2023.09.15.557802. bioRxiv. 2023. PMID: 37745612 Free PMC article. Preprint.
Conditional Dependency of LP-184 on Prostaglandin Reductase 1 is Synthetic Lethal in Pancreatic Cancers with DNA Damage Repair Deficiencies.
Restifo D, McDermott JR, Cvetkovic D, Dos Santos T, Ogier C, Surumbayeva A, Handorf EA, Schimke C, Ma C, Cai KQ, Olszanski AJ, Kathad U, Bhatia K, Sharma P, Kulkarni A, Astsaturov I. Restifo D, et al. Mol Cancer Ther. 2023 Oct 2;22(10):1182-1190. doi: 10.1158/1535-7163.MCT-22-0818. Mol Cancer Ther. 2023. PMID: 37552607 Free PMC article.
Tumor-Suppressive and Immune-Stimulating Roles of Cholesterol 25-hydroxylase in Pancreatic Cancer Cells.
McBrearty N, Cho C, Chen J, Zahedi F, Peck AR, Radaelli E, Assenmacher CA, Pavlak C, Devine A, Yu P, Lu Z, Zhang H, Li J, Pitarresi JR, Astsaturov I, Cukierman E, Rustgi AK, Stanger BZ, Rui H, Fuchs SY. McBrearty N, et al. Mol Cancer Res. 2023 Mar 1;21(3):228-239. doi: 10.1158/1541-7786.MCR-22-0602. Mol Cancer Res. 2023. PMID: 36378658 Free PMC article.
NetrinG1+ cancer-associated fibroblasts generate unique extracellular vesicles that support the survival of pancreatic cancer cells under nutritional stress.
Raghavan KS, Francescone R, Franco-Barraza J, Gardiner JC, Vendramini-Costa DB, Luong T, Pourmandi N, Andren A, Kurimchak A, Ogier C, Campbell PM, Duncan JS, Lyssiotis CA, Languino LR, Cukierman E. Raghavan KS, et al. Cancer Res Commun. 2022 Sep;2(9):1017-1036. doi: 10.1158/2767-9764.crc-21-0147. Epub 2022 Sep 19. Cancer Res Commun. 2022. PMID: 36310768 Free PMC article.
21 results