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Table representation of search results timeline featuring number of search results per year.
Year | Number of Results |
---|---|
2016 | 2 |
2017 | 4 |
2018 | 2 |
2019 | 4 |
2021 | 1 |
2024 | 0 |
Search Results
7 results
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Page 1
Selective and noncovalent targeting of RAS mutants for inhibition and degradation.
Nat Commun. 2021 May 11;12(1):2656. doi: 10.1038/s41467-021-22969-5.
Nat Commun. 2021.
PMID: 33976200
Free PMC article.
Targeting the α4-α5 dimerization interface of K-RAS inhibits tumor formation in vivo.
Khan I, Spencer-Smith R, O'Bryan JP.
Khan I, et al.
Oncogene. 2019 Apr;38(16):2984-2993. doi: 10.1038/s41388-018-0636-y. Epub 2018 Dec 20.
Oncogene. 2019.
PMID: 30573767
Free PMC article.
Item in Clipboard
Pharmacological targeting of RAS: Recent success with direct inhibitors.
O'Bryan JP.
O'Bryan JP.
Pharmacol Res. 2019 Jan;139:503-511. doi: 10.1016/j.phrs.2018.10.021. Epub 2018 Oct 23.
Pharmacol Res. 2019.
PMID: 30366101
Free PMC article.
Review.
Item in Clipboard
Direct inhibition of RAS: Quest for the Holy Grail?
Spencer-Smith R, O'Bryan JP.
Spencer-Smith R, et al.
Semin Cancer Biol. 2019 Feb;54:138-148. doi: 10.1016/j.semcancer.2017.12.005. Epub 2017 Dec 14.
Semin Cancer Biol. 2019.
PMID: 29248537
Free PMC article.
Review.
Item in Clipboard
Targeting the α4-α5 interface of RAS results in multiple levels of inhibition.
Spencer-Smith R, Li L, Prasad S, Koide A, Koide S, O'Bryan JP.
Spencer-Smith R, et al.
Small GTPases. 2019 Sep;10(5):378-387. doi: 10.1080/21541248.2017.1333188. Epub 2017 Dec 31.
Small GTPases. 2019.
PMID: 28692342
Free PMC article.
Item in Clipboard
Inhibition of RAS function through targeting an allosteric regulatory site.
Spencer-Smith R, Koide A, Zhou Y, Eguchi RR, Sha F, Gajwani P, Santana D, Gupta A, Jacobs M, Herrero-Garcia E, Cobbert J, Lavoie H, Smith M, Rajakulendran T, Dowdell E, Okur MN, Dementieva I, Sicheri F, Therrien M, Hancock JF, Ikura M, Koide S, O'Bryan JP.
Spencer-Smith R, et al.
Nat Chem Biol. 2017 Jan;13(1):62-68. doi: 10.1038/nchembio.2231. Epub 2016 Nov 7.
Nat Chem Biol. 2017.
PMID: 27820802
Free PMC article.
Item in Clipboard
Intersectin scaffold proteins and their role in cell signaling and endocytosis.
Herrero-Garcia E, O'Bryan JP.
Herrero-Garcia E, et al.
Biochim Biophys Acta Mol Cell Res. 2017 Jan;1864(1):23-30. doi: 10.1016/j.bbamcr.2016.10.005. Epub 2016 Oct 12.
Biochim Biophys Acta Mol Cell Res. 2017.
PMID: 27746143
Free PMC article.
Review.
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