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Cytotoxic CD4 development requires CD4 effectors to concurrently recognize local antigen and encounter type I IFN-induced IL-15.
Cell Rep. 2023 Oct 31;42(10):113182. doi: 10.1016/j.celrep.2023.113182. Epub 2023 Sep 29.
Cell Rep. 2023.
PMID: 37776519
Free PMC article.
CD4 Effector TCR Avidity for Peptide on APC Determines the Level of Memory Generated.
Jones MC, Castonguay C, Nanaware PP, Weaver GC, Stadinski B, Kugler-Umana OA, Huseby ES, Stern LJ, McKinstry KK, Strutt TM, Devarajan P, Swain SL.
Jones MC, et al.
J Immunol. 2023 Jun 15;210(12):1950-1961. doi: 10.4049/jimmunol.2200337.
J Immunol. 2023.
PMID: 37093656
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