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Year | Number of Results |
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2020 | 1 |
2021 | 1 |
2022 | 2 |
2023 | 2 |
2024 | 1 |
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Inhibition of multiple staphylococcal growth states by a small molecule that disrupts membrane fluidity and voltage.
mSphere. 2024 Mar 26;9(3):e0077223. doi: 10.1128/msphere.00772-23. Epub 2024 Mar 6.
mSphere. 2024.
PMID: 38445864
Free PMC article.
Bacterial efflux pump modulators prevent bacterial growth in macrophages and under broth conditions that mimic the host environment.
Allgood SC, Su C-C, Crooks AL, Meyer CT, Zhou B, Betterton MD, Barbachyn MR, Yu EW, Detweiler CS.
Allgood SC, et al.
mBio. 2023 Nov 3;14(6):e0249223. doi: 10.1128/mbio.02492-23. Online ahead of print.
mBio. 2023.
PMID: 37921493
Free PMC article.
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Bacterial Efflux Pump Modulators Prevent Bacterial Growth in Macrophages and Under Broth Conditions that Mimic the Host Environment.
Allgood SC, Su CC, Crooks AL, Meyer CT, Zhou B, Betterton MD, Barbachyn MR, Yu EW, Detweiler CS.
Allgood SC, et al.
bioRxiv [Preprint]. 2023 Sep 20:2023.09.20.558466. doi: 10.1101/2023.09.20.558466.
bioRxiv. 2023.
PMID: 37786697
Free PMC article.
Updated.
Preprint.
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Salmonella enterica Infections Are Disrupted by Two Small Molecules That Accumulate within Phagosomes and Differentially Damage Bacterial Inner Membranes.
Villanueva JA, Crooks AL, Nagy TA, Quintana JLJ, Dalebroux ZD, Detweiler CS.
Villanueva JA, et al.
mBio. 2022 Oct 26;13(5):e0179022. doi: 10.1128/mbio.01790-22. Epub 2022 Sep 22.
mBio. 2022.
PMID: 36135367
Free PMC article.
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A small molecule that disrupts S. Typhimurium membrane voltage without cell lysis reduces bacterial colonization of mice.
Dombach JL, Quintana JL, Allgood SC, Nagy TA, Gustafson DL, Detweiler CS.
Dombach JL, et al.
PLoS Pathog. 2022 Jun 10;18(6):e1010606. doi: 10.1371/journal.ppat.1010606. eCollection 2022 Jun.
PLoS Pathog. 2022.
PMID: 35687608
Free PMC article.
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Staphylococcal Bacterial Persister Cells, Biofilms, and Intracellular Infection Are Disrupted by JD1, a Membrane-Damaging Small Molecule.
Dombach JL, Quintana JLJ, Detweiler CS.
Dombach JL, et al.
mBio. 2021 Oct 26;12(5):e0180121. doi: 10.1128/mBio.01801-21. Epub 2021 Oct 12.
mBio. 2021.
PMID: 34634935
Free PMC article.
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A small molecule that mitigates bacterial infection disrupts Gram-negative cell membranes and is inhibited by cholesterol and neutral lipids.
Dombach JL, Quintana JLJ, Nagy TA, Wan C, Crooks AL, Yu H, Su CC, Yu EW, Shen J, Detweiler CS.
Dombach JL, et al.
PLoS Pathog. 2020 Dec 8;16(12):e1009119. doi: 10.1371/journal.ppat.1009119. eCollection 2020 Dec.
PLoS Pathog. 2020.
PMID: 33290418
Free PMC article.
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