R21 AI151363/AI/NIAID NIH HHS/United States[Grants and Funding] - Search Results

Year	Number of Results
2020	1
2021	9
2022	9
2023	3
2024	2

1

Bacteriophage and antibiotic combination therapy for recurrent Enterococcus faecium bacteremia.

Stellfox ME, Fernandes C, Shields RK, Haidar G, Hughes Kramer K, Dembinski E, Mangalea MR, Arya G, Canfield GS, Duerkop BA, Van Tyne D. Stellfox ME, et al. mBio. 2024 Mar 13;15(3):e0339623. doi: 10.1128/mbio.03396-23. Epub 2024 Feb 14. mBio. 2024. PMID: 38353560 Free PMC article.

2

Differential in vitro susceptibility to ampicillin/ceftriaxone combination therapy among Enterococcus faecalis infective endocarditis clinical isolates.

Westbrook KJ, Chilambi GS, Stellfox ME, Nordstrom HR, Li Y, Iovleva A, Shah NH, Jones CE, Kline EG, Squires KM, Miller WR, Tran TT, Arias CA, Doi Y, Shields RK, Van Tyne D. Westbrook KJ, et al. J Antimicrob Chemother. 2024 Apr 2;79(4):801-809. doi: 10.1093/jac/dkae032. J Antimicrob Chemother. 2024. PMID: 38334390

3

Mutations in ompK36 differentially impact in vitro synergy of meropenem/vaborbactam and ceftazidime/avibactam in combination with other antibiotics against KPC-producing Klebsiella pneumoniae.

Rogers TM, Kline EG, Griffith MP, Jones CE, Rubio AM, Squires KM, Shields RK. Rogers TM, et al. JAC Antimicrob Resist. 2023 Oct 26;5(5):dlad113. doi: 10.1093/jacamr/dlad113. eCollection 2023 Oct. JAC Antimicrob Resist. 2023. PMID: 37901589 Free PMC article.

4

Early initiation of three-drug combinations for the treatment of carbapenem-resistant A. baumannii among COVID-19 patients.

Heil EL, Claeys KC, Kline EG, Rogers TM, Squires KM, Iovleva A, Doi Y, Banoub M, Noval MM, Luethy PM, Shields RK. Heil EL, et al. J Antimicrob Chemother. 2023 Apr 3;78(4):1034-1040. doi: 10.1093/jac/dkad042. J Antimicrob Chemother. 2023. PMID: 36869724 Free PMC article.

5

Optimal ceftazidime/avibactam dosing exposure against KPC-producing Klebsiella pneumoniae.

Tam VH, Merlau PR, Hudson CS, Kline EG, Eales BM, Smith J, Sofjan AK, Shields RK. Tam VH, et al. J Antimicrob Chemother. 2022 Oct 28;77(11):3130-3137. doi: 10.1093/jac/dkac294. J Antimicrob Chemother. 2022. PMID: 36031868 Free PMC article.

6

Evolution and Transmission of Cefiderocol-Resistant Acinetobacter baumannii During an Outbreak in the Burn Intensive Care Unit.

Smoke SM, Brophy A, Reveron S, Iovleva A, Kline EG, Marano M, Miller LP, Shields RK. Smoke SM, et al. Clin Infect Dis. 2023 Feb 8;76(3):e1261-e1265. doi: 10.1093/cid/ciac647. Clin Infect Dis. 2023. PMID: 35974429 Free PMC article.

7

Genomic characterization of lytic bacteriophages targeting genetically diverse Pseudomonas aeruginosa clinical isolates.

Nordstrom HR, Evans DR, Finney AG, Westbrook KJ, Zamora PF, Hofstaedter CE, Yassin MH, Pradhan A, Iovleva A, Ernst RK, Bomberger JM, Shields RK, Doi Y, Van Tyne D. Nordstrom HR, et al. iScience. 2022 May 10;25(6):104372. doi: 10.1016/j.isci.2022.104372. eCollection 2022 Jun 17. iScience. 2022. PMID: 35620437 Free PMC article.

8

Different Conformations Revealed by NMR Underlie Resistance to Ceftazidime/Avibactam and Susceptibility to Meropenem and Imipenem among D179Y Variants of KPC β-Lactamase.

Taracila MA, Bethel CR, Hujer AM, Papp-Wallace KM, Barnes MD, Rutter JD, VanPelt J, Shurina BA, van den Akker F, Clancy CJ, Nguyen MH, Cheng S, Shields RK, Page RC, Bonomo RA. Taracila MA, et al. Antimicrob Agents Chemother. 2022 Apr 19;66(4):e0212421. doi: 10.1128/aac.02124-21. Epub 2022 Mar 21. Antimicrob Agents Chemother. 2022. PMID: 35311523 Free PMC article.

9

Convergent Evolution of Antibiotic Tolerance in Patients with Persistent Methicillin-Resistant Staphylococcus aureus Bacteremia.

Elgrail MM, Chen E, Shaffer MG, Srinivasa V, Griffith MP, Mustapha MM, Shields RK, Van Tyne D, Culyba MJ. Elgrail MM, et al. Infect Immun. 2022 Apr 21;90(4):e0000122. doi: 10.1128/iai.00001-22. Epub 2022 Mar 14. Infect Immun. 2022. PMID: 35285704 Free PMC article.

10

Cefiderocol for the Treatment of Infections Due to Metallo-B-lactamase-Producing Pathogens in the CREDIBLE-CR and APEKS-NP Phase 3 Randomized Studies.

Timsit JF, Paul M, Shields RK, Echols R, Baba T, Yamano Y, Portsmouth S. Timsit JF, et al. Clin Infect Dis. 2022 Sep 29;75(6):1081-1084. doi: 10.1093/cid/ciac078. Clin Infect Dis. 2022. PMID: 35148378 Free PMC article. Clinical Trial.

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