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Table representation of search results timeline featuring number of search results per year.
Year | Number of Results |
---|---|
2017 | 1 |
2018 | 1 |
2019 | 1 |
2020 | 1 |
2022 | 1 |
2023 | 2 |
2024 | 0 |
Search Results
7 results
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Page 1
Covalent Macrocyclic Proteasome Inhibitors Mitigate Resistance in Plasmodium falciparum.
ACS Infect Dis. 2023 Oct 13;9(10):2036-2047. doi: 10.1021/acsinfecdis.3c00310. Epub 2023 Sep 15.
ACS Infect Dis. 2023.
PMID: 37712594
Mitigating the risk of antimalarial resistance via covalent dual-subunit inhibition of the Plasmodium proteasome.
Deni I, Stokes BH, Ward KE, Fairhurst KJ, Pasaje CFA, Yeo T, Akbar S, Park H, Muir R, Bick DS, Zhan W, Zhang H, Liu YJ, Ng CL, Kirkman LA, Almaliti J, Gould AE, Duffey M, O'Donoghue AJ, Uhlemann AC, Niles JC, da Fonseca PCA, Gerwick WH, Lin G, Bogyo M, Fidock DA.
Deni I, et al.
Cell Chem Biol. 2023 May 18;30(5):470-485.e6. doi: 10.1016/j.chembiol.2023.03.002. Epub 2023 Mar 23.
Cell Chem Biol. 2023.
PMID: 36963402
Free PMC article.
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Mutant PfCRT Can Mediate Piperaquine Resistance in African Plasmodium falciparum With Reduced Fitness and Increased Susceptibility to Other Antimalarials.
Wicht KJ, Small-Saunders JL, Hagenah LM, Mok S, Fidock DA.
Wicht KJ, et al.
J Infect Dis. 2022 Nov 28;226(11):2021-2029. doi: 10.1093/infdis/jiac365.
J Infect Dis. 2022.
PMID: 36082431
Free PMC article.
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Plasmodium berghei K13 Mutations Mediate In Vivo Artemisinin Resistance That Is Reversed by Proteasome Inhibition.
Simwela NV, Stokes BH, Aghabi D, Bogyo M, Fidock DA, Waters AP.
Simwela NV, et al.
mBio. 2020 Nov 10;11(6):e02312-20. doi: 10.1128/mBio.02312-20.
mBio. 2020.
PMID: 33173001
Free PMC article.
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Covalent Plasmodium falciparum-selective proteasome inhibitors exhibit a low propensity for generating resistance in vitro and synergize with multiple antimalarial agents.
Stokes BH, Yoo E, Murithi JM, Luth MR, Afanasyev P, da Fonseca PCA, Winzeler EA, Ng CL, Bogyo M, Fidock DA.
Stokes BH, et al.
PLoS Pathog. 2019 Jun 6;15(6):e1007722. doi: 10.1371/journal.ppat.1007722. eCollection 2019 Jun.
PLoS Pathog. 2019.
PMID: 31170268
Free PMC article.
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Defining the Determinants of Specificity of Plasmodium Proteasome Inhibitors.
Yoo E, Stokes BH, de Jong H, Vanaerschot M, Kumar T, Lawrence N, Njoroge M, Garcia A, Van der Westhuyzen R, Momper JD, Ng CL, Fidock DA, Bogyo M.
Yoo E, et al.
J Am Chem Soc. 2018 Sep 12;140(36):11424-11437. doi: 10.1021/jacs.8b06656. Epub 2018 Aug 29.
J Am Chem Soc. 2018.
PMID: 30107725
Free PMC article.
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Protein Degradation Systems as Antimalarial Therapeutic Targets.
Ng CL, Fidock DA, Bogyo M.
Ng CL, et al.
Trends Parasitol. 2017 Sep;33(9):731-743. doi: 10.1016/j.pt.2017.05.009. Epub 2017 Jul 5.
Trends Parasitol. 2017.
PMID: 28688800
Free PMC article.
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