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Human Neutrophil Peptide 1 Limits Hypercholesterolemia-induced Atherosclerosis by Increasing Hepatic LDL Clearance.
Paulin N, Döring Y, Kooijman S, Blanchet X, Viola JR, de Jong R, Mandl M, Hendrikse J, Schiener M, von Hundelshausen P, Vogt A, Weber C, Bdeir K, Hofmann SM, Rensen PCN, Drechsler M, Soehnlein O. Paulin N, et al. EBioMedicine. 2017 Feb;16:204-211. doi: 10.1016/j.ebiom.2017.01.006. Epub 2017 Jan 7. EBioMedicine. 2017. PMID: 28111237 Free PMC article.
Urokinase-type Plasminogen Activator (uPA) Promotes Angiogenesis by Attenuating Proline-rich Homeodomain Protein (PRH) Transcription Factor Activity and De-repressing Vascular Endothelial Growth Factor (VEGF) Receptor Expression.
Stepanova V, Jayaraman PS, Zaitsev SV, Lebedeva T, Bdeir K, Kershaw R, Holman KR, Parfyonova YV, Semina EV, Beloglazova IB, Tkachuk VA, Cines DB. Stepanova V, et al. J Biol Chem. 2016 Jul 15;291(29):15029-45. doi: 10.1074/jbc.M115.678490. Epub 2016 May 4. J Biol Chem. 2016. PMID: 27151212 Free PMC article.
DNA vaccines targeting heavy chain C-terminal fragments of Clostridium botulinum neurotoxin serotypes A, B, and E induce potent humoral and cellular immunity and provide protection from lethal toxin challenge.
Scott VL, Villarreal DO, Hutnick NA, Walters JN, Ragwan E, Bdeir K, Yan J, Sardesai NY, Finnefrock AC, Casimiro DR, Weiner DB. Scott VL, et al. Hum Vaccin Immunother. 2015;11(8):1961-71. doi: 10.1080/21645515.2015.1066051. Hum Vaccin Immunother. 2015. PMID: 26158319 Free PMC article.
Developmental endothelial locus-1 is a homeostatic factor in the central nervous system limiting neuroinflammation and demyelination.
Choi EY, Lim JH, Neuwirth A, Economopoulou M, Chatzigeorgiou A, Chung KJ, Bittner S, Lee SH, Langer H, Samus M, Kim H, Cho GS, Ziemssen T, Bdeir K, Chavakis E, Koh JY, Boon L, Hosur K, Bornstein SR, Meuth SG, Hajishengallis G, Chavakis T. Choi EY, et al. Mol Psychiatry. 2015 Jul;20(7):880-888. doi: 10.1038/mp.2014.146. Epub 2014 Nov 11. Mol Psychiatry. 2015. PMID: 25385367 Free PMC article.