R21 AI084714/AI/NIAID NIH HHS/United States[Grants and Funding] - Search Results

Year	Number of Results
2010	1
2011	2
2012	2
2013	3
2014	2
2024	0

1

Broad and potent HIV-1 neutralization by a human antibody that binds the gp41-gp120 interface.

Huang J, Kang BH, Pancera M, Lee JH, Tong T, Feng Y, Imamichi H, Georgiev IS, Chuang GY, Druz A, Doria-Rose NA, Laub L, Sliepen K, van Gils MJ, de la Peña AT, Derking R, Klasse PJ, Migueles SA, Bailer RT, Alam M, Pugach P, Haynes BF, Wyatt RT, Sanders RW, Binley JM, Ward AB, Mascola JR, Kwong PD, Connors M. Huang J, et al. Nature. 2014 Nov 6;515(7525):138-42. doi: 10.1038/nature13601. Epub 2014 Sep 3. Nature. 2014. PMID: 25186731 Free PMC article.

2

Multi-Parameter Exploration of HIV-1 Virus-Like Particles as Neutralizing Antibody Immunogens in Guinea Pigs, Rabbits and Macaques.

Tong T, Crooks ET, Osawa K, Robinson JE, Barnes M, Apetrei C, Binley JM. Tong T, et al. Virology. 2014 May;456-457:55-69. doi: 10.1016/j.virol.2014.03.015. Virology. 2014. PMID: 24882891 Free PMC article.

3

A human antibody to the CD4 binding site of gp120 capable of highly potent but sporadic cross clade neutralization of primary HIV-1.

Gach JS, Quendler H, Tong T, Narayan KM, Du SX, Whalen RG, Binley JM, Forthal DN, Poignard P, Zwick MB. Gach JS, et al. PLoS One. 2013 Aug 26;8(8):e72054. doi: 10.1371/journal.pone.0072054. eCollection 2013. PLoS One. 2013. PMID: 23991039 Free PMC article.

4

Comparative Immunogenicity of Evolved V1V2-Deleted HIV-1 Envelope Glycoprotein Trimers.

Bontjer I, Melchers M, Tong T, van Montfort T, Eggink D, Montefiori D, Olson WC, Moore JP, Binley JM, Berkhout B, Sanders RW. Bontjer I, et al. PLoS One. 2013 Jun 26;8(6):e67484. doi: 10.1371/journal.pone.0067484. Print 2013. PLoS One. 2013. PMID: 23840716 Free PMC article.

5

Topological analysis of HIV-1 glycoproteins expressed in situ on virus surfaces reveals tighter packing but greater conformational flexibility than for soluble gp120.

Tong T, Osawa K, Robinson JE, Crooks ET, Binley JM. Tong T, et al. J Virol. 2013 Aug;87(16):9233-49. doi: 10.1128/JVI.01145-13. Epub 2013 Jun 5. J Virol. 2013. PMID: 23740975 Free PMC article.

6

HIV-1 virus-like particles bearing pure env trimers expose neutralizing epitopes but occlude nonneutralizing epitopes.

Tong T, Crooks ET, Osawa K, Binley JM. Tong T, et al. J Virol. 2012 Apr;86(7):3574-87. doi: 10.1128/JVI.06938-11. Epub 2012 Feb 1. J Virol. 2012. PMID: 22301141 Free PMC article.

7

Targeting HIV-1 envelope glycoprotein trimers to B cells by using APRIL improves antibody responses.

Melchers M, Bontjer I, Tong T, Chung NP, Klasse PJ, Eggink D, Montefiori DC, Gentile M, Cerutti A, Olson WC, Berkhout B, Binley JM, Moore JP, Sanders RW. Melchers M, et al. J Virol. 2012 Mar;86(5):2488-500. doi: 10.1128/JVI.06259-11. Epub 2011 Dec 28. J Virol. 2012. PMID: 22205734 Free PMC article.

8

Enzyme digests eliminate nonfunctional Env from HIV-1 particle surfaces, leaving native Env trimers intact and viral infectivity unaffected.

Crooks ET, Tong T, Osawa K, Binley JM. Crooks ET, et al. J Virol. 2011 Jun;85(12):5825-39. doi: 10.1128/JVI.00154-11. Epub 2011 Apr 6. J Virol. 2011. PMID: 21471242 Free PMC article.

9

Role of complex carbohydrates in human immunodeficiency virus type 1 infection and resistance to antibody neutralization.

Binley JM, Ban YE, Crooks ET, Eggink D, Osawa K, Schief WR, Sanders RW. Binley JM, et al. J Virol. 2010 Jun;84(11):5637-55. doi: 10.1128/JVI.00105-10. Epub 2010 Mar 24. J Virol. 2010. PMID: 20335257 Free PMC article.

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