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β-hydroxybutyrate administered at reperfusion reduces infarct size and preserves cardiac function by improving mitochondrial function through autophagy in male mice.
Chu Y, Hua Y, He L, He J, Chen Y, Yang J, Mahmoud I, Zeng F, Zeng X, Benavides GA, Darley-Usmar VM, Young ME, Ballinger SW, Prabhu SD, Zhang C, Xie M. Chu Y, et al. J Mol Cell Cardiol. 2024 Jan;186:31-44. doi: 10.1016/j.yjmcc.2023.11.001. Epub 2023 Nov 16. J Mol Cell Cardiol. 2024. PMID: 37979443
miR-486 is essential for muscle function and suppresses a dystrophic transcriptome.
Samani A, Hightower RM, Reid AL, English KG, Lopez MA, Doyle JS, Conklin MJ, Schneider DA, Bamman MM, Widrick JJ, Crossman DK, Xie M, Jee D, Lai EC, Alexander MS. Samani A, et al. Life Sci Alliance. 2022 May 5;5(9):e202101215. doi: 10.26508/lsa.202101215. Print 2022 Sep. Life Sci Alliance. 2022. PMID: 35512829 Free PMC article.
Activation of Autophagic Flux Blunts Cardiac Ischemia/Reperfusion Injury.
Xie M, Cho GW, Kong Y, Li DL, Altamirano F, Luo X, Morales CR, Jiang N, Schiattarella GG, May HI, Medina J, Shelton JM, Ferdous A, Gillette TG, Hill JA. Xie M, et al. Circ Res. 2021 Jul 23;129(3):435-450. doi: 10.1161/CIRCRESAHA.120.318601. Epub 2021 Jun 11. Circ Res. 2021. PMID: 34111934 Free PMC article.