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Protein arginine methyltransferase 5 (PRMT5) inhibition induces lymphoma cell death through reactivation of the retinoblastoma tumor suppressor pathway and polycomb repressor complex 2 (PRC2) silencing.
Chung J, Karkhanis V, Tae S, Yan F, Smith P, Ayers LW, Agostinelli C, Pileri S, Denis GV, Baiocchi RA, Sif S. Chung J, et al. J Biol Chem. 2013 Dec 6;288(49):35534-47. doi: 10.1074/jbc.M113.510669. Epub 2013 Nov 4. J Biol Chem. 2013. PMID: 24189068 Free PMC article.
Parallel imaging microfluidic cytometer.
Ehrlich DJ, McKenna BK, Evans JG, Belkina AC, Denis GV, Sherr DH, Cheung MC. Ehrlich DJ, et al. Methods Cell Biol. 2011;102:49-75. doi: 10.1016/B978-0-12-374912-3.00003-1. Methods Cell Biol. 2011. PMID: 21704835 Free PMC article. Review.
Obesity genes and insulin resistance.
Belkina AC, Denis GV. Belkina AC, et al. Curr Opin Endocrinol Diabetes Obes. 2010 Oct;17(5):472-7. doi: 10.1097/MED.0b013e32833c5c48. Curr Opin Endocrinol Diabetes Obes. 2010. PMID: 20585247 Free PMC article. Review.