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Year Number of Results
2015 1
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2017 4
2018 241
2019 267
2020 265
2021 489
2022 368
2023 173
2024 241

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1,825 results

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Page 1
Direct transposition of native DNA for sensitive multimodal single-molecule sequencing.
Nanda AS, Wu K, Irkliyenko I, Woo B, Ostrowski MS, Clugston AS, Sayles LC, Xu L, Satpathy AT, Nguyen HG, Alejandro Sweet-Cordero E, Goodarzi H, Kasinathan S, Ramani V. Nanda AS, et al. Nat Genet. 2024 May 9. doi: 10.1038/s41588-024-01748-0. Online ahead of print. Nat Genet. 2024. PMID: 38724748
We developed two methods that implement tagmentation and use 90-99% less input than current protocols: (1) single-molecule real-time sequencing by tagmentation (SMRT-Tag), which allows detection of genetic variation and CpG methylation; and (2) single-molecule adenine-methylated …
We developed two methods that implement tagmentation and use 90-99% less input than current protocols: (1) single-molecule real-time sequenc …
Genetic regulation of human brain proteome reveals proteins implicated in psychiatric disorders.
Luo J, Li L, Niu M, Kong D, Jiang Y, Poudel S, Shieh AW, Cheng L, Giase G, Grennan K, White KP, Chen C, Wang SH, Pinto D, Wang Y, Liu C, Peng J, Wang X. Luo J, et al. Mol Psychiatry. 2024 May 9. doi: 10.1038/s41380-024-02576-8. Online ahead of print. Mol Psychiatry. 2024. PMID: 38724566
Genome-wide association studies have identified hundreds of genomic susceptibility loci with susceptibility to psychiatric disorders; however, the contribution of these loci to the underlying psychopathology and etiology remains elusive. Here we generated deep human brain …
Genome-wide association studies have identified hundreds of genomic susceptibility loci with susceptibility to psychiatric disorders; howeve …
Repression of developmental transcription factor networks triggers aging-associated gene expression in human glial progenitor cells.
Mariani JN, Mansky B, Madsen PM, Salinas D, Kesmen D, Huynh NPT, Kuypers NJ, Kesel ER, Bates J, Payne C, Chandler-Militello D, Benraiss A, Goldman SA. Mariani JN, et al. Nat Commun. 2024 May 8;15(1):3873. doi: 10.1038/s41467-024-48118-2. Nat Commun. 2024. PMID: 38719882 Free PMC article.
Human glial progenitor cells (hGPCs) exhibit diminished expansion competence with age, as well as after recurrent demyelination. ...
Human glial progenitor cells (hGPCs) exhibit diminished expansion competence with age, as well as after recurrent demyelination. ...
Mononuclear phagocyte morphologic response to chemoattractants is dependent on geranylgeranyl pyrophosphate.
Krauklis SA, Hussain J, Murphy KM, Dray EL, Ousley CG, Justyna K, Distefano MD, Steelman AJ, McKim DB. Krauklis SA, et al. Am J Physiol Endocrinol Metab. 2024 May 8. doi: 10.1152/ajpendo.00359.2023. Online ahead of print. Am J Physiol Endocrinol Metab. 2024. PMID: 38717364
Proteomic analysis of C15AlkOPP-prenylated proteins identified several geranylgeranylated proteins involved in chemoattractant responses, including RHOA, RAC1, CDC42, and GNG2. Chemoattractant responses in THP-1 human macrophages were also geranylgeranylation dependent. Th …
Proteomic analysis of C15AlkOPP-prenylated proteins identified several geranylgeranylated proteins involved in chemoattractant responses, in …
Structural basis for the intracellular regulation of ferritin degradation.
Hoelzgen F, Nguyen TTP, Klukin E, Boumaiza M, Srivastava AK, Kim EY, Zalk R, Shahar A, Cohen-Schwartz S, Meyron-Holtz EG, Bou-Abdallah F, Mancias JD, Frank GA. Hoelzgen F, et al. Nat Commun. 2024 May 7;15(1):3802. doi: 10.1038/s41467-024-48151-1. Nat Commun. 2024. PMID: 38714719 Free PMC article.
1,825 results