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Strain-induced mechanotransduction through primary cilia, extracellular ATP, purinergic calcium signaling, and ERK1/2 transactivates CITED2 and downregulates MMP-1 and MMP-13 gene expression in chondrocytes.
Osteoarthritis Cartilage. 2016 May;24(5):892-901. doi: 10.1016/j.joca.2015.11.015. Epub 2015 Dec 12.
Osteoarthritis Cartilage. 2016.
PMID: 26687824
Free article.
Green tea polyphenol treatment is chondroprotective, anti-inflammatory and palliative in a mouse post-traumatic osteoarthritis model.
Leong DJ, Choudhury M, Hanstein R, Hirsh DM, Kim SJ, Majeska RJ, Schaffler MB, Hardin JA, Spray DC, Goldring MB, Cobelli NJ, Sun HB.
Leong DJ, et al.
Arthritis Res Ther. 2014 Dec 17;16(6):508. doi: 10.1186/s13075-014-0508-y.
Arthritis Res Ther. 2014.
PMID: 25516005
Free PMC article.
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