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2021 3
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CRISPR editing of CCR5 and HIV-1 facilitates viral elimination in antiretroviral drug-suppressed virus-infected humanized mice.
Dash PK, Chen C, Kaminski R, Su H, Mancuso P, Sillman B, Zhang C, Liao S, Sravanam S, Liu H, Waight E, Guo L, Mathews S, Sariyer R, Mosley RL, Poluektova LY, Caocci M, Amini S, Gorantla S, Burdo TH, Edagwa B, Gendelman HE, Khalili K. Dash PK, et al. Proc Natl Acad Sci U S A. 2023 May 9;120(19):e2217887120. doi: 10.1073/pnas.2217887120. Epub 2023 May 1. Proc Natl Acad Sci U S A. 2023. PMID: 37126704 Free PMC article.
Multipolymer microsphere delivery of SARS-CoV-2 antigens.
Shahjin F, Patel M, Machhi J, Cohen JD, Nayan MU, Yeapuri P, Zhang C, Waight E, Hasan M, Abdelmoaty MM, Dash PK, Zhou Y, Andreu I, Gendelman HE, Kevadiya BD. Shahjin F, et al. Acta Biomater. 2023 Mar 1;158:493-509. doi: 10.1016/j.actbio.2022.12.043. Epub 2022 Dec 26. Acta Biomater. 2023. PMID: 36581007 Free PMC article.
Animal models for studies of HIV-1 brain reservoirs.
Waight E, Zhang C, Mathews S, Kevadiya BD, Lloyd KCK, Gendelman HE, Gorantla S, Poluektova LY, Dash PK. Waight E, et al. J Leukoc Biol. 2022 Nov;112(5):1285-1295. doi: 10.1002/JLB.5VMR0322-161R. Epub 2022 Aug 31. J Leukoc Biol. 2022. PMID: 36044375 Free PMC article. Review.
Transformation of dolutegravir into an ultra-long-acting parenteral prodrug formulation.
Deodhar S, Sillman B, Bade AN, Avedissian SN, Podany AT, McMillan JM, Gautam N, Hanson B, Dyavar Shetty BL, Szlachetka A, Johnston M, Thurman M, Munt DJ, Dash AK, Markovic M, Dahan A, Alnouti Y, Yazdi A, Kevadiya BD, Byrareddy SN, Cohen SM, Edagwa B, Gendelman HE. Deodhar S, et al. Nat Commun. 2022 Jun 9;13(1):3226. doi: 10.1038/s41467-022-30902-7. Nat Commun. 2022. PMID: 35680875 Free PMC article.
CRISPR-Cas9 Mediated Exonic Disruption for HIV-1 Elimination.
Herskovitz J, Hasan M, Patel M, Blomberg WR, Cohen JD, Machhi J, Shahjin F, Mosley RL, McMillan J, Kevadiya BD, Gendelman HE. Herskovitz J, et al. EBioMedicine. 2021 Nov;73:103678. doi: 10.1016/j.ebiom.2021.103678. Epub 2021 Nov 10. EBioMedicine. 2021. PMID: 34774454 Free PMC article.
Ultra-long-acting (XLA) antivirals for chronic viral hepatitis.
Soriano V, Alvarez C, Edagwa B, de Mendoza C, Montoya N, Treviño A, Gendelman H. Soriano V, et al. Int J Infect Dis. 2022 Jan;114:45-50. doi: 10.1016/j.ijid.2021.10.052. Epub 2021 Oct 30. Int J Infect Dis. 2022. PMID: 34728344 Free PMC article.