R01 NS117176/NS/NINDS NIH HHS/United States[Grants and Funding] - Search Results

Year	Number of Results
2020	1
2021	1
2022	6
2023	3
2024	1

1

Pathogenicity Prediction of GABA_A Receptor Missense Variants.

Wang YJ, Vu GH, Mu TW. Wang YJ, et al. bioRxiv [Preprint]. 2023 Nov 16:2023.11.14.567135. doi: 10.1101/2023.11.14.567135. bioRxiv. 2023. PMID: 38014242 Free PMC article. Preprint.

2

Adapting the endoplasmic reticulum proteostasis rescues epilepsy-associated NMDA receptor variants.

Zhang PP, Benske TM, Ahn LY, Schaffer AE, Paton JC, Paton AW, Mu TW, Wang YJ. Zhang PP, et al. Acta Pharmacol Sin. 2024 Feb;45(2):282-297. doi: 10.1038/s41401-023-01172-w. Epub 2023 Oct 6. Acta Pharmacol Sin. 2024. PMID: 37803141

3

Pharmacological chaperones restore proteostasis of epilepsy-associated GABA_A receptor variants.

Wang YJ, Seibert H, Ahn LY, Schaffer AE, Mu TW. Wang YJ, et al. bioRxiv [Preprint]. 2023 Apr 19:2023.04.18.537383. doi: 10.1101/2023.04.18.537383. bioRxiv. 2023. PMID: 37131660 Free PMC article. Preprint.

4

Anti-seizure mechanisms of midazolam and valproate at the β2(L51M) variant of the GABA_A receptor.

Kuanyshbek A, Wang M, Andersson Å, Tuifua M, Palmer EE, Sachdev RK, Mu TW, Vetter I, Keramidas A. Kuanyshbek A, et al. Neuropharmacology. 2022 Dec 15;221:109295. doi: 10.1016/j.neuropharm.2022.109295. Epub 2022 Oct 17. Neuropharmacology. 2022. PMID: 36257447 Free PMC article.

5

Quantitative interactome proteomics identifies a proteostasis network for GABA_A receptors.

Wang YJ, Di XJ, Mu TW. Wang YJ, et al. J Biol Chem. 2022 Oct;298(10):102423. doi: 10.1016/j.jbc.2022.102423. Epub 2022 Aug 27. J Biol Chem. 2022. PMID: 36030824 Free PMC article.

6

The endoplasmic reticulum membrane complex promotes proteostasis of GABA_A receptors.

Whittsette AL, Wang YJ, Mu TW. Whittsette AL, et al. iScience. 2022 Jul 13;25(8):104754. doi: 10.1016/j.isci.2022.104754. eCollection 2022 Aug 19. iScience. 2022. PMID: 35938049 Free PMC article.

7

Protein quality control of N-methyl-D-aspartate receptors.

Benske TM, Mu TW, Wang YJ. Benske TM, et al. Front Cell Neurosci. 2022 Jul 22;16:907560. doi: 10.3389/fncel.2022.907560. eCollection 2022. Front Cell Neurosci. 2022. PMID: 35936491 Free PMC article. Review.

8

Stress-induced perturbations in intracellular amino acids reprogram mRNA translation in osmoadaptation independently of the ISR.

Krokowski D, Jobava R, Szkop KJ, Chen CW, Fu X, Venus S, Guan BJ, Wu J, Gao Z, Banaszuk W, Tchorzewski M, Mu T, Ropelewski P, Merrick WC, Mao Y, Sevval AI, Miranda H, Qian SB, Manifava M, Ktistakis NT, Vourekas A, Jankowsky E, Topisirovic I, Larsson O, Hatzoglou M. Krokowski D, et al. Cell Rep. 2022 Jul 19;40(3):111092. doi: 10.1016/j.celrep.2022.111092. Cell Rep. 2022. PMID: 35858571 Free PMC article.

9

Pharmacological activation of ATF6 remodels the proteostasis network to rescue pathogenic GABA_A receptors.

Wang M, Cotter E, Wang YJ, Fu X, Whittsette AL, Lynch JW, Wiseman RL, Kelly JW, Keramidas A, Mu TW. Wang M, et al. Cell Biosci. 2022 Apr 27;12(1):48. doi: 10.1186/s13578-022-00783-w. Cell Biosci. 2022. PMID: 35477478 Free PMC article.

10

Proteostasis Regulators Restore Function of Epilepsy-Associated GABA_A Receptors.

Di XJ, Wang YJ, Cotter E, Wang M, Whittsette AL, Han DY, Sangwung P, Brown R, Lynch JW, Keramidas A, Mu TW. Di XJ, et al. Cell Chem Biol. 2021 Jan 21;28(1):46-59.e7. doi: 10.1016/j.chembiol.2020.08.012. Epub 2020 Sep 3. Cell Chem Biol. 2021. PMID: 32888501 Free PMC article.

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