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Modification of lipid rafts by extracellular vesicles carrying HIV-1 protein Nef induces redistribution of amyloid precursor protein and Tau, causing neuronal dysfunction.
Ditiatkovski M, Mukhamedova N, Dragoljevic D, Hoang A, Low H, Pushkarsky T, Fu Y, Carmichael I, Hill AF, Murphy AJ, Bukrinsky M, Sviridov D. Ditiatkovski M, et al. J Biol Chem. 2020 Sep 18;295(38):13377-13392. doi: 10.1074/jbc.RA120.014642. Epub 2020 Jul 30. J Biol Chem. 2020. PMID: 32732283 Free PMC article.
Exosomes containing HIV protein Nef reorganize lipid rafts potentiating inflammatory response in bystander cells.
Mukhamedova N, Hoang A, Dragoljevic D, Dubrovsky L, Pushkarsky T, Low H, Ditiatkovski M, Fu Y, Ohkawa R, Meikle PJ, Horvath A, Brichacek B, Miller YI, Murphy A, Bukrinsky M, Sviridov D. Mukhamedova N, et al. PLoS Pathog. 2019 Jul 25;15(7):e1007907. doi: 10.1371/journal.ppat.1007907. eCollection 2019 Jul. PLoS Pathog. 2019. PMID: 31344124 Free PMC article.
Modelling interaction between HIV-1 Nef and calnexin.
Adzhubei AA, Anashkina AA, Tkachev YV, Kravatsky YV, Pushkarsky T, Kulkarni A, Makarov AA, Bukrinsky MI. Adzhubei AA, et al. AIDS. 2018 Sep 24;32(15):2103-2111. doi: 10.1097/QAD.0000000000001951. AIDS. 2018. PMID: 30005006 Free PMC article.