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Page 1
GDNF-expressing macrophages restore motor functions at a severe late-stage, and produce long-term neuroprotective effects at an early-stage of Parkinson's disease in transgenic Parkin Q311X(A) mice.
Zhao Y, Haney MJ, Jin YS, Uvarov O, Vinod N, Lee YZ, Langworthy B, Fine JP, Rodriguez M, El-Hage N, Kabanov AV, Batrakova EV. Zhao Y, et al. J Control Release. 2019 Dec 10;315:139-149. doi: 10.1016/j.jconrel.2019.10.027. Epub 2019 Oct 31. J Control Release. 2019. PMID: 31678095 Free PMC article.
Macrophages with cellular backpacks for targeted drug delivery to the brain.
Klyachko NL, Polak R, Haney MJ, Zhao Y, Gomes Neto RJ, Hill MC, Kabanov AV, Cohen RE, Rubner MF, Batrakova EV. Klyachko NL, et al. Biomaterials. 2017 Sep;140:79-87. doi: 10.1016/j.biomaterials.2017.06.017. Epub 2017 Jun 18. Biomaterials. 2017. PMID: 28633046 Free PMC article.
Development of exosome-encapsulated paclitaxel to overcome MDR in cancer cells.
Kim MS, Haney MJ, Zhao Y, Mahajan V, Deygen I, Klyachko NL, Inskoe E, Piroyan A, Sokolsky M, Okolie O, Hingtgen SD, Kabanov AV, Batrakova EV. Kim MS, et al. Nanomedicine. 2016 Apr;12(3):655-664. doi: 10.1016/j.nano.2015.10.012. Epub 2015 Nov 14. Nanomedicine. 2016. PMID: 26586551 Free PMC article.
Exosomes as drug delivery vehicles for Parkinson's disease therapy.
Haney MJ, Klyachko NL, Zhao Y, Gupta R, Plotnikova EG, He Z, Patel T, Piroyan A, Sokolsky M, Kabanov AV, Batrakova EV. Haney MJ, et al. J Control Release. 2015 Jun 10;207:18-30. doi: 10.1016/j.jconrel.2015.03.033. Epub 2015 Mar 31. J Control Release. 2015. PMID: 25836593 Free PMC article.
Macrophages offer a paradigm switch for CNS delivery of therapeutic proteins.
Klyachko NL, Haney MJ, Zhao Y, Manickam DS, Mahajan V, Suresh P, Hingtgen SD, Mosley RL, Gendelman HE, Kabanov AV, Batrakova EV. Klyachko NL, et al. Nanomedicine (Lond). 2014 Jul;9(9):1403-22. doi: 10.2217/nnm.13.115. Epub 2013 Nov 18. Nanomedicine (Lond). 2014. PMID: 24237263 Free PMC article.
25 results