R01 HL155431/HL/NHLBI NIH HHS/United States[Grants and Funding] - Search Results

Year	Number of Results
2021	4
2022	4
2023	7
2024	3

1

Cholesterol trafficking to the ER leads to the activation of CaMKII/JNK/NLRP3 and promotes atherosclerosis.

Yalcinkaya M, Liu W, Xiao T, Abramowicz S, Wang R, Wang N, Westerterp M, Tall AR. Yalcinkaya M, et al. J Lipid Res. 2024 Apr;65(4):100534. doi: 10.1016/j.jlr.2024.100534. Epub 2024 Mar 22. J Lipid Res. 2024. PMID: 38522750 Free PMC article.

2

Suppression of IL-1β promotes beneficial accumulation of fibroblast-like cells in atherosclerotic plaques in clonal hematopoiesis.

Fidler TP, Dunbar A, Kim E, Hardaway B, Pauli J, Xue C, Abramowicz S, Xiao T, O'Connor K, Sachs N, Wang N, Maegdefessel L, Levine R, Reilly M, Tall AR. Fidler TP, et al. Nat Cardiovasc Res. 2024 Jan;3(1):60-75. doi: 10.1038/s44161-023-00405-9. Epub 2024 Jan 11. Nat Cardiovasc Res. 2024. PMID: 38362011 Free PMC article.

3

Jak2 V617F clonal hematopoiesis promotes arterial thrombosis via platelet activation and cross talk.

Liu W, Pircher J, Schuermans A, Ul Ain Q, Zhang Z, Honigberg MC, Yalcinkaya M, Nakao T, Pournamadri A, Xiao T, Hajebrahimi MA, Wasner L, Stegner D, Petzold T, Natarajan P, Massberg S, Tall AR, Schulz C, Wang N. Liu W, et al. Blood. 2024 Apr 11;143(15):1539-1550. doi: 10.1182/blood.2023022260. Blood. 2024. PMID: 38142422

4

BRCC3-Mediated NLRP3 Deubiquitylation Promotes Inflammasome Activation and Atherosclerosis in Tet2 Clonal Hematopoiesis.

Yalcinkaya M, Liu W, Thomas LA, Olszewska M, Xiao T, Abramowicz S, Papapetrou EP, Westerterp M, Wang N, Tabas I, Tall AR. Yalcinkaya M, et al. Circulation. 2023 Nov 28;148(22):1764-1777. doi: 10.1161/CIRCULATIONAHA.123.065344. Epub 2023 Oct 2. Circulation. 2023. PMID: 37781816

5

Blockade of IL-6 signaling alleviates atherosclerosis in Tet2-deficient clonal hematopoiesis.

Liu W, Yalcinkaya M, Maestre IF, Olszewska M, Ampomah PB, Heimlich JB, Wang R, Vela PS, Xiao T, Bick AG, Levine R, Papapetrou EP, Libby P, Tabas I, Wang N, Tall AR. Liu W, et al. Nat Cardiovasc Res. 2023 Jun;2(6):572-586. doi: 10.1038/s44161-023-00281-3. Epub 2023 Jun 8. Nat Cardiovasc Res. 2023. PMID: 37539077 Free PMC article.

6

Genetic modification of inflammation- and clonal hematopoiesis-associated cardiovascular risk.

Yu Z, Fidler TP, Ruan Y, Vlasschaert C, Nakao T, Uddin MM, Mack T, Niroula A, Heimlich JB, Zekavat SM, Gibson CJ, Griffin GK, Wang Y, Peloso GM, Heard-Costa N, Levy D, Vasan RS, Aguet F, Ardlie KG, Taylor KD, Rich SS, Rotter JI, Libby P, Jaiswal S, Ebert BL, Bick AG, Tall AR, Natarajan P. Yu Z, et al. J Clin Invest. 2023 Sep 15;133(18):e168597. doi: 10.1172/JCI168597. J Clin Invest. 2023. PMID: 37498674 Free PMC article.

7

Inflammasomes and Atherosclerosis: a Mixed Picture.

Tall AR, Bornfeldt KE. Tall AR, et al. Circ Res. 2023 May 26;132(11):1505-1520. doi: 10.1161/CIRCRESAHA.123.321637. Epub 2023 May 25. Circ Res. 2023. PMID: 37228237 Review.

8

Hematopoietic NLRP3 and AIM2 Inflammasomes Promote Diabetes-Accelerated Atherosclerosis, but Increased Necrosis Is Independent of Pyroptosis.

Hsu CC, Fidler TP, Kanter JE, Kothari V, Kramer F, Tang J, Tall AR, Bornfeldt KE. Hsu CC, et al. Diabetes. 2023 Jul 1;72(7):999-1011. doi: 10.2337/db22-0962. Diabetes. 2023. PMID: 37083999

9

Clonal hematopoiesis and ischemic stroke.

Wang N, Tall AR. Wang N, et al. Blood. 2023 Feb 16;141(7):693-694. doi: 10.1182/blood.2022019177. Blood. 2023. PMID: 36795449 Free PMC article. No abstract available.

10

Cholesterol accumulation in macrophages drives NETosis in atherosclerotic plaques via IL-1β secretion.

Yalcinkaya M, Fotakis P, Liu W, Endo-Umeda K, Dou H, Abramowicz S, Xiao T, Libby P, Wang N, Tall AR, Westerterp M. Yalcinkaya M, et al. Cardiovasc Res. 2023 May 2;119(4):969-981. doi: 10.1093/cvr/cvac189. Cardiovasc Res. 2023. PMID: 36537208 Free PMC article.

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