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2022 7
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BIN1 knockdown rescues systolic dysfunction in aging male mouse hearts.
Westhoff M, Del Villar SG, Voelker TL, Thai PN, Spooner HC, Costa AD, Sirish P, Chiamvimonvat N, Dickson EJ, Dixon RE. Westhoff M, et al. Nat Commun. 2024 Apr 25;15(1):3528. doi: 10.1038/s41467-024-47847-8. Nat Commun. 2024. PMID: 38664444 Free PMC article.
A deep learning platform to assess drug proarrhythmia risk.
Serrano R, Feyen DAM, Bruyneel AAN, Hnatiuk AP, Vu MM, Amatya PL, Perea-Gil I, Prado M, Seeger T, Wu JC, Karakikes I, Mercola M. Serrano R, et al. Cell Stem Cell. 2023 Jan 5;30(1):86-95.e4. doi: 10.1016/j.stem.2022.12.002. Epub 2022 Dec 22. Cell Stem Cell. 2023. PMID: 36563695 Free PMC article.
Reengineering Ponatinib to Minimize Cardiovascular Toxicity.
Hnatiuk AP, Bruyneel AAN, Tailor D, Pandrala M, Dheeraj A, Li W, Serrano R, Feyen DAM, Vu MM, Amatya P, Gupta S, Nakauchi Y, Morgado I, Wiebking V, Liao R, Porteus MH, Majeti R, Malhotra SV, Mercola M. Hnatiuk AP, et al. Cancer Res. 2022 Aug 3;82(15):2777-2791. doi: 10.1158/0008-5472.CAN-21-3652. Cancer Res. 2022. PMID: 35763671 Free PMC article.
Serine biosynthesis as a novel therapeutic target for dilated cardiomyopathy.
Perea-Gil I, Seeger T, Bruyneel AAN, Termglinchan V, Monte E, Lim EW, Vadgama N, Furihata T, Gavidia AA, Arthur Ataam J, Bharucha N, Martinez-Amador N, Ameen M, Nair P, Serrano R, Kaur B, Feyen DAM, Diecke S, Snyder MP, Metallo CM, Mercola M, Karakikes I. Perea-Gil I, et al. Eur Heart J. 2022 Sep 21;43(36):3477-3489. doi: 10.1093/eurheartj/ehac305. Eur Heart J. 2022. PMID: 35728000 Free PMC article.