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2018 2
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2020 1
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2024 1

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Targeting PRMT9-mediated arginine methylation suppresses cancer stem cell maintenance and elicits cGAS-mediated anticancer immunity.
Dong H, He X, Zhang L, Chen W, Lin YC, Liu SB, Wang H, Nguyen LXT, Li M, Zhu Y, Zhao D, Ghoda L, Serody J, Vincent B, Luznik L, Gojo I, Zeidner J, Su R, Chen J, Sharma R, Pirrotte P, Wu X, Hu W, Han W, Shen B, Kuo YH, Jin J, Salhotra A, Wang J, Marcucci G, Luo YL, Li L. Dong H, et al. Nat Cancer. 2024 Apr;5(4):601-624. doi: 10.1038/s43018-024-00736-x. Epub 2024 Feb 27. Nat Cancer. 2024. PMID: 38413714 Free PMC article.
TET2 deficiency promotes MDS-associated leukemogenesis.
Huang F, Sun J, Chen W, Zhang L, He X, Dong H, Wu Y, Wang H, Li Z, Ball B, Khaled S, Marcucci G, Li L. Huang F, et al. Blood Cancer J. 2022 Oct 4;12(10):141. doi: 10.1038/s41408-022-00739-w. Blood Cancer J. 2022. PMID: 36195586 Free PMC article. No abstract available.
HDAC4 inhibition disrupts TET2 function in high-risk MDS and AML.
Huang F, Sun J, Chen W, He X, Zhu Y, Dong H, Wang H, Li Z, Zhang L, Khaled S, Marcucci G, Huang J, Li L. Huang F, et al. Aging (Albany NY). 2020 Jul 29;12(17):16759-16774. doi: 10.18632/aging.103605. Epub 2020 Jul 29. Aging (Albany NY). 2020. PMID: 32726753 Free PMC article.
PRMT1-mediated FLT3 arginine methylation promotes maintenance of FLT3-ITD+ acute myeloid leukemia.
He X, Zhu Y, Lin YC, Li M, Du J, Dong H, Sun J, Zhu L, Wang H, Ding Z, Zhang L, Zhang L, Zhao D, Wang Z, Wu H, Zhang H, Jiang W, Xu Y, Jin J, Shen Y, Perry J, Zhao X, Zhang B, Liu S, Xue SL, Shen B, Chen CW, Chen J, Khaled S, Kuo YH, Marcucci G, Luo Y, Li L. He X, et al. Blood. 2019 Aug 8;134(6):548-560. doi: 10.1182/blood.2019001282. Epub 2019 Jun 19. Blood. 2019. PMID: 31217189 Free PMC article.
Role of SIRT1 in hematologic malignancies.
Huang FT, Sun J, Zhang L, He X, Zhu YH, Dong HJ, Wang HY, Zhu L, Zou JY, Huang JW, Li L. Huang FT, et al. J Zhejiang Univ Sci B. 2019 May;20(5):391-398. doi: 10.1631/jzus.B1900148. J Zhejiang Univ Sci B. 2019. PMID: 31090265 Free PMC article. Review.
SIRT1 Activation Disrupts Maintenance of Myelodysplastic Syndrome Stem and Progenitor Cells by Restoring TET2 Function.
Sun J, He X, Zhu Y, Ding Z, Dong H, Feng Y, Du J, Wang H, Wu X, Zhang L, Yu X, Lin A, McDonald T, Zhao D, Wu H, Hua WK, Zhang B, Feng L, Tohyama K, Bhatia R, Oberdoerffer P, Chung YJ, Aplan PD, Boultwood J, Pellagatti A, Khaled S, Kortylewski M, Pichiorri F, Kuo YH, Carlesso N, Marcucci G, Jin H, Li L. Sun J, et al. Cell Stem Cell. 2018 Sep 6;23(3):355-369.e9. doi: 10.1016/j.stem.2018.07.018. Epub 2018 Aug 23. Cell Stem Cell. 2018. PMID: 30146412 Free PMC article.
Impact of FLT3-ITD length on prognosis of acute myeloid leukemia.
Liu SB, Dong HJ, Bao XB, Qiu QC, Li HZ, Shen HJ, Ding ZX, Wang C, Chu XL, Yu JQ, Tao T, Li Z, Tang XW, Chen SN, Wu DP, Li L, Xue SL. Liu SB, et al. Haematologica. 2019 Jan;104(1):e9-e12. doi: 10.3324/haematol.2018.191809. Epub 2018 Aug 3. Haematologica. 2019. PMID: 30076182 Free PMC article. No abstract available.