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A nanoparticle probe for the imaging of autophagic flux in live mice via magnetic resonance and near-infrared fluorescence.
Chen HH, Khatun Z, Wei L, Mekkaoui C, Patel D, Kim SJW, Boukhalfa A, Enoma E, Meng L, Chen YI, Kaikkonen L, Li G, Capen DE, Sahu P, Kumar ATN, Blanton RM, Yuan H, Das S, Josephson L, Sosnovik DE. Chen HH, et al. Nat Biomed Eng. 2022 Sep;6(9):1045-1056. doi: 10.1038/s41551-022-00904-3. Epub 2022 Jul 11. Nat Biomed Eng. 2022. PMID: 35817962 Free PMC article.
The mitochondrial regulator PGC1α is induced by cGMP-PKG signaling and mediates the protective effects of phosphodiesterase 5 inhibition in heart failure.
Zhu G, Ueda K, Hashimoto M, Zhang M, Sasaki M, Kariya T, Sasaki H, Kaludercic N, Lee DI, Bedja D, Gabrielson M, Yuan Y, Paolocci N, Blanton RM, Karas RH, Mendelsohn ME, O'Rourke B, Kass DA, Takimoto E. Zhu G, et al. FEBS Lett. 2022 Jan;596(1):17-28. doi: 10.1002/1873-3468.14228. Epub 2021 Nov 19. FEBS Lett. 2022. PMID: 34778969 Free PMC article.
MLK3 mediates impact of PKG1α on cardiac function and controls blood pressure through separate mechanisms.
Calamaras TD, Pande S, Baumgartner RA, Kim SK, McCarthy JC, Martin GL, Tam K, McLaughlin AL, Wang GR, Aronovitz MJ, Lin W, Aguirre JI, Baca P, Liu P, Richards DA, Davis RJ, Karas RH, Jaffe IZ, Blanton RM. Calamaras TD, et al. JCI Insight. 2021 Sep 22;6(18):e149075. doi: 10.1172/jci.insight.149075. JCI Insight. 2021. PMID: 34324442 Free PMC article.
cGMP Signaling and Modulation in Heart Failure.
Blanton RM. Blanton RM. J Cardiovasc Pharmacol. 2020 May;75(5):385-398. doi: 10.1097/FJC.0000000000000749. J Cardiovasc Pharmacol. 2020. PMID: 31464774 Free PMC article. Review.
21 results