R01 HL052141/HL/NHLBI NIH HHS/United States[Grants and Funding] - Search Results

Year	Number of Results
1999	1
2001	1
2006	1
2007	5
2008	2
2009	3
2010	11
2011	13
2012	9
2013	9
2014	1
2015	2
2016	12
2017	6
2018	2
2019	6
2020	1
2021	1
2022	4
2023	1
2024	0

1

Targeting an allosteric site in dynamin-related protein 1 to inhibit Fis1-mediated mitochondrial dysfunction.

Rios L, Pokhrel S, Li SJ, Heo G, Haileselassie B, Mochly-Rosen D. Rios L, et al. Nat Commun. 2023 Jul 19;14(1):4356. doi: 10.1038/s41467-023-40043-0. Nat Commun. 2023. PMID: 37468472 Free PMC article.

2

A Selective Inhibitor of Cardiac Troponin I Phosphorylation by Delta Protein Kinase C (δPKC) as a Treatment for Ischemia-Reperfusion Injury.

Qvit N, Lin AJ, Elezaby A, Ostberg NP, Campos JC, Ferreira JCB, Mochly-Rosen D. Qvit N, et al. Pharmaceuticals (Basel). 2022 Feb 22;15(3):271. doi: 10.3390/ph15030271. Pharmaceuticals (Basel). 2022. PMID: 35337069 Free PMC article.

3

Drp1/Fis1-Dependent Pathologic Fission and Associated Damaged Extracellular Mitochondria Contribute to Macrophage Dysfunction in Endotoxin Tolerance.

Mukherjee R, Tompkins CA, Ostberg NP, Joshi AU, Massis LM, Vijayan V, Gera K, Monack D, Cornell TT, Hall MW, Mochly-Rosen D, Haileselassie B. Mukherjee R, et al. Crit Care Med. 2022 Jun 1;50(6):e504-e515. doi: 10.1097/CCM.0000000000005437. Epub 2022 Jan 24. Crit Care Med. 2022. PMID: 35067534 Free PMC article.

4

Mitochondrial Fusion, Fission, and Mitophagy in Cardiac Diseases: Challenges and Therapeutic Opportunities.

Scheffer DDL, Garcia AA, Lee L, Mochly-Rosen D, Ferreira JCB. Scheffer DDL, et al. Antioxid Redox Signal. 2022 May;36(13-15):844-863. doi: 10.1089/ars.2021.0145. Epub 2022 Apr 18. Antioxid Redox Signal. 2022. PMID: 35044229 Free PMC article. Review.

5

δPKC-Mediated DRP1 Phosphorylation Impacts Macrophage Mitochondrial Function and Inflammatory Response to Endotoxin.

Lin AJ, Joshi AU, Mukherjee R, Tompkins CA, Vijayan V, Mochly-Rosen D, Haileselassie B. Lin AJ, et al. Shock. 2022 Mar 1;57(3):435-443. doi: 10.1097/SHK.0000000000001885. Shock. 2022. PMID: 34738957 Free PMC article.

6

Author Correction: Fragmented mitochondria released from microglia trigger A1 astrocytic response and propagate inflammatory neurodegeneration.

Joshi AU, Minhas PS, Liddelow SA, Haileselassie B, Andreasson KI, Dorn GW 2nd, Mochly-Rosen D. Joshi AU, et al. Nat Neurosci. 2021 Feb;24(2):289. doi: 10.1038/s41593-020-00774-5. Nat Neurosci. 2021. PMID: 33324000 No abstract available.

7

Mitochondrial dysfunction mediated through dynamin-related protein 1 (Drp1) propagates impairment in blood brain barrier in septic encephalopathy.

Haileselassie B, Joshi AU, Minhas PS, Mukherjee R, Andreasson KI, Mochly-Rosen D. Haileselassie B, et al. J Neuroinflammation. 2020 Jan 27;17(1):36. doi: 10.1186/s12974-019-1689-8. J Neuroinflammation. 2020. PMID: 31987040 Free PMC article.

8

Unlocking the Secrets of Mitochondria in the Cardiovascular System: Path to a Cure in Heart Failure—A Report from the 2018 National Heart, Lung, and Blood Institute Workshop.

Tian R, Colucci WS, Arany Z, Bachschmid MM, Ballinger SW, Boudina S, Bruce JE, Busija DW, Dikalov S, Dorn GW II, Galis ZS, Gottlieb RA, Kelly DP, Kitsis RN, Kohr MJ, Levy D, Lewandowski ED, McClung JM, Mochly-Rosen D, O'Brien KD, O'Rourke B, Park JY, Ping P, Sack MN, Sheu SS, Shi Y, Shiva S, Wallace DC, Weiss RG, Vernon HJ, Wong R, Schwartz Longacre L. Tian R, et al. Circulation. 2019 Oct 1;140(14):1205-1216. doi: 10.1161/CIRCULATIONAHA.119.040551. Circulation. 2019. PMID: 31769940 Free PMC article. Review.

9

Fragmented mitochondria released from microglia trigger A1 astrocytic response and propagate inflammatory neurodegeneration.

Joshi AU, Minhas PS, Liddelow SA, Haileselassie B, Andreasson KI, Dorn GW 2nd, Mochly-Rosen D. Joshi AU, et al. Nat Neurosci. 2019 Oct;22(10):1635-1648. doi: 10.1038/s41593-019-0486-0. Epub 2019 Sep 23. Nat Neurosci. 2019. PMID: 31551592 Free PMC article.

10

Proteasome-Dependent Regulation of Distinct Metabolic States During Long-Term Culture of Human iPSC-Derived Cardiomyocytes.

Ebert A, Joshi AU, Andorf S, Dai Y, Sampathkumar S, Chen H, Li Y, Garg P, Toischer K, Hasenfuss G, Mochly-Rosen D, Wu JC. Ebert A, et al. Circ Res. 2019 Jun 21;125(1):90-103. doi: 10.1161/CIRCRESAHA.118.313973. Epub 2019 May 20. Circ Res. 2019. PMID: 31104567 Free PMC article.

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