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2021 4
2022 2
2023 4
2024 3

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Chemical Catalysis Guides Structural Identification for the Major In Vivo Metabolite of the BET Inhibitor JQ1.
Holmes S, Jain P, Rodriguez KG, Williams J, Yu Z, Cerda-Smith C, Samuel ELG, Campbell J, Hakenjos JM, Monsivais D, Li F, Chamakuri S, Matzuk MM, Santini C, MacKenzie KR, Young DW. Holmes S, et al. ACS Med Chem Lett. 2024 Jan 2;15(1):107-115. doi: 10.1021/acsmedchemlett.3c00464. eCollection 2024 Jan 11. ACS Med Chem Lett. 2024. PMID: 38229743 Free PMC article.
An acetylation-mediated chromatin switch governs H3K4 methylation read-write capability.
Jain K, Marunde MR, Burg JM, Gloor SL, Joseph FM, Poncha KF, Gillespie ZB, Rodriguez KL, Popova IK, Hall NW, Vaidya A, Howard SA, Taylor HF, Mukhsinova L, Onuoha UC, Patteson EF, Cooke SW, Taylor BC, Weinzapfel EN, Cheek MA, Meiners MJ, Fox GC, Namitz KEW, Cowles MW, Krajewski K, Sun ZW, Cosgrove MS, Young NL, Keogh MC, Strahl BD. Jain K, et al. Elife. 2023 May 19;12:e82596. doi: 10.7554/eLife.82596. Elife. 2023. PMID: 37204295 Free PMC article.
High-throughput profiling of histone post-translational modifications and chromatin modifying proteins by reverse phase protein array.
Wang X, Shi Z, Lu HY, Kim JJ, Bu W, Villalobos JA, Perera DN, Jung SY, Wang T, Grimm SL, Taylor BC, Rajapakshe K, Park H, Wulfkuhle J, Young NL, Li Y, Coarfa C, Edwards DP, Huang S. Wang X, et al. J Proteomics. 2022 Jun 30;262:104596. doi: 10.1016/j.jprot.2022.104596. Epub 2022 Apr 27. J Proteomics. 2022. PMID: 35489683 Free PMC article.
Histone variant-specific post-translational modifications.
Joseph FM, Young NL. Joseph FM, et al. Semin Cell Dev Biol. 2023 Feb 15;135:73-84. doi: 10.1016/j.semcdb.2022.02.012. Epub 2022 Mar 9. Semin Cell Dev Biol. 2023. PMID: 35277331 Free PMC article. Review.
Gene therapy using Aβ variants for amyloid reduction.
Park KW, Wood CA, Li J, Taylor BC, Oh S, Young NL, Jankowsky JL. Park KW, et al. Mol Ther. 2021 Jul 7;29(7):2294-2307. doi: 10.1016/j.ymthe.2021.02.026. Epub 2021 Feb 27. Mol Ther. 2021. PMID: 33647457 Free PMC article.
12 results