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Two-pore channels regulate endomembrane tension to enable remodeling and resolution of phagolysosomes.
Proc Natl Acad Sci U S A. 2024 Feb 20;121(8):e2309465121. doi: 10.1073/pnas.2309465121. Epub 2024 Feb 14.
Proc Natl Acad Sci U S A. 2024.
PMID: 38354262
The SARS-CoV-2 accessory protein Orf3a is not an ion channel, but does interact with trafficking proteins.
Miller AN, Houlihan PR, Matamala E, Cabezas-Bratesco D, Lee GY, Cristofori-Armstrong B, Dilan TL, Sanchez-Martinez S, Matthies D, Yan R, Yu Z, Ren D, Brauchi SE, Clapham DE.
Miller AN, et al.
Elife. 2023 Jan 25;12:e84477. doi: 10.7554/eLife.84477.
Elife. 2023.
PMID: 36695574
Free PMC article.
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A growth-factor-activated lysosomal K+ channel regulates Parkinson's pathology.
Wie J, Liu Z, Song H, Tropea TF, Yang L, Wang H, Liang Y, Cang C, Aranda K, Lohmann J, Yang J, Lu B, Chen-Plotkin AS, Luk KC, Ren D.
Wie J, et al.
Nature. 2021 Mar;591(7850):431-437. doi: 10.1038/s41586-021-03185-z. Epub 2021 Jan 27.
Nature. 2021.
PMID: 33505021
Free PMC article.
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Lipid-gated monovalent ion fluxes regulate endocytic traffic and support immune surveillance.
Freeman SA, Uderhardt S, Saric A, Collins RF, Buckley CM, Mylvaganam S, Boroumand P, Plumb J, Germain RN, Ren D, Grinstein S.
Freeman SA, et al.
Science. 2020 Jan 17;367(6475):301-305. doi: 10.1126/science.aaw9544. Epub 2019 Dec 5.
Science. 2020.
PMID: 31806695
Free PMC article.
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