R01 GM130145/GM/NIGMS NIH HHS/United States[Grants and Funding] - Search Results

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Subject: R01 GM130145/GM/NIGMS NIH HHS/United States[Grant - PubMed

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Year	Number of Results
2018	1
2019	1
2020	1
2022	1
2023	3
2024	1

8 results

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The p97/VCP adaptor UBXD1 drives AAA+ remodeling and ring opening through multi-domain tethered interactions.

Braxton JR, Altobelli CR, Tucker MR, Tse E, Thwin AC, Arkin MR, Southworth DR. Braxton JR, et al. Nat Struct Mol Biol. 2023 Dec;30(12):2009-2019. doi: 10.1038/s41594-023-01126-0. Epub 2023 Nov 9. Nat Struct Mol Biol. 2023. PMID: 37945741 Free PMC article.

Synthetic autophagy receptor.

Jiang Z, Kuo YH, Arkin MR. Jiang Z, et al. Autophagy. 2024 Mar;20(3):701-703. doi: 10.1080/15548627.2023.2278954. Epub 2024 Feb 14. Autophagy. 2024. PMID: 37934826

Autophagy Receptor-Inspired Antibody-Fusion Proteins for Targeted Intracellular Degradation.

Jiang Z, Kuo YH, Arkin MR. Jiang Z, et al. J Am Chem Soc. 2023 Nov 8;145(44):23939-23947. doi: 10.1021/jacs.3c05199. Epub 2023 Sep 25. J Am Chem Soc. 2023. PMID: 37748140 Free PMC article.

The p97/VCP adapter UBXD1 drives AAA+ remodeling and ring opening through multi-domain tethered interactions.

Braxton JR, Altobelli CR, Tucker MR, Tse E, Thwin AC, Arkin MR, Southworth DR. Braxton JR, et al. bioRxiv [Preprint]. 2023 May 15:2023.05.15.540864. doi: 10.1101/2023.05.15.540864. bioRxiv. 2023. PMID: 37292947 Free PMC article. Updated. Preprint.

Adaptor-Specific Antibody Fragment Inhibitors for the Intracellular Modulation of p97 (VCP) Protein-Protein Interactions.

Jiang Z, Kuo YH, Zhong M, Zhang J, Zhou XX, Xing L, Wells JA, Wang Y, Arkin MR. Jiang Z, et al. J Am Chem Soc. 2022 Jul 27;144(29):13218-13225. doi: 10.1021/jacs.2c03665. Epub 2022 Jul 12. J Am Chem Soc. 2022. PMID: 35819848 Free PMC article.

Multiparametric High-Content Assays to Measure Cell Health and Oxidative Damage as a Model for Drug-Induced Liver Injury.

Pohan G, Espinosa JA, Chen S, Ang KK, Arkin MR, Markossian S. Pohan G, et al. Curr Protoc Chem Biol. 2020 Dec;12(4):e90. doi: 10.1002/cpch.90. Curr Protoc Chem Biol. 2020. PMID: 33315311 Free PMC article.

Modulating protein-protein interaction networks in protein homeostasis.

Zhong M, Lee GM, Sijbesma E, Ottmann C, Arkin MR. Zhong M, et al. Curr Opin Chem Biol. 2019 Jun;50:55-65. doi: 10.1016/j.cbpa.2019.02.012. Epub 2019 Mar 23. Curr Opin Chem Biol. 2019. PMID: 30913483 Free PMC article. Review.

Optimization of Phenyl Indole Inhibitors of the AAA+ ATPase p97.

LaPorte MG, Burnett JC, Colombo R, Bulfer SL, Alverez C, Chou TF, Neitz RJ, Green N, Moore WJ, Yue Z, Li S, Arkin MR, Wipf P, Huryn DM. LaPorte MG, et al. ACS Med Chem Lett. 2018 Sep 18;9(11):1075-1081. doi: 10.1021/acsmedchemlett.8b00372. eCollection 2018 Nov 8. ACS Med Chem Lett. 2018. PMID: 30429948 Free PMC article.

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