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Yeast EndoG prevents genome instability by degrading cytoplasmic DNA.
Yu Y, Wang X, Fox J, Yu R, Thakre P, McCauley B, Nikoloutsos N, Li Q, Hastings PJ, Dang W, Chen K, Ira G. Yu Y, et al. Res Sq [Preprint]. 2024 Jan 5:rs.3.rs-3641411. doi: 10.21203/rs.3.rs-3641411/v1. Res Sq. 2024. PMID: 38260641 Free PMC article. Preprint.
Tracking break-induced replication shows that it stalls at roadblocks.
Liu L, Yan Z, Osia BA, Twarowski J, Sun L, Kramara J, Lee RS, Kumar S, Elango R, Li H, Dang W, Ira G, Malkova A. Liu L, et al. Nature. 2021 Feb;590(7847):655-659. doi: 10.1038/s41586-020-03172-w. Epub 2021 Jan 20. Nature. 2021. PMID: 33473214 Free PMC article.
Rad52 Restrains Resection at DNA Double-Strand Break Ends in Yeast.
Yan Z, Xue C, Kumar S, Crickard JB, Yu Y, Wang W, Pham N, Li Y, Niu H, Sung P, Greene EC, Ira G. Yan Z, et al. Mol Cell. 2019 Dec 5;76(5):699-711.e6. doi: 10.1016/j.molcel.2019.08.017. Epub 2019 Sep 18. Mol Cell. 2019. PMID: 31542296 Free PMC article.
Guidelines for DNA recombination and repair studies: Cellular assays of DNA repair pathways.
Klein HL, Bačinskaja G, Che J, Cheblal A, Elango R, Epshtein A, Fitzgerald DM, Gómez-González B, Khan SR, Kumar S, Leland BA, Marie L, Mei Q, Miné-Hattab J, Piotrowska A, Polleys EJ, Putnam CD, Radchenko EA, Saada AA, Sakofsky CJ, Shim EY, Stracy M, Xia J, Yan Z, Yin Y, Aguilera A, Argueso JL, Freudenreich CH, Gasser SM, Gordenin DA, Haber JE, Ira G, Jinks-Robertson S, King MC, Kolodner RD, Kuzminov A, Lambert SA, Lee SE, Miller KM, Mirkin SM, Petes TD, Rosenberg SM, Rothstein R, Symington LS, Zawadzki P, Kim N, Lisby M, Malkova A. Klein HL, et al. Microb Cell. 2019 Jan 7;6(1):1-64. doi: 10.15698/mic2019.01.664. Microb Cell. 2019. PMID: 30652105 Free PMC article. Review.