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2017 2
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trans-Translation inhibitors bind to a novel site on the ribosome and clear Neisseria gonorrhoeae in vivo.
Aron ZD, Mehrani A, Hoffer ED, Connolly KL, Srinivas P, Torhan MC, Alumasa JN, Cabrera M, Hosangadi D, Barbor JS, Cardinale SC, Kwasny SM, Morin LR, Butler MM, Opperman TJ, Bowlin TL, Jerse A, Stagg SM, Dunham CM, Keiler KC. Aron ZD, et al. Nat Commun. 2021 Mar 19;12(1):1799. doi: 10.1038/s41467-021-22012-7. Nat Commun. 2021. PMID: 33741965 Free PMC article.
Pathogen-specific antimicrobials engineered de novo through membrane-protein biomimicry.
Simonson AW, Mongia AS, Aronson MR, Alumasa JN, Chan DC, Lawanprasert A, Howe MD, Bolotsky A, Mal TK, George C, Ebrahimi A, Baughn AD, Proctor EA, Keiler KC, Medina SH. Simonson AW, et al. Nat Biomed Eng. 2021 May;5(5):467-480. doi: 10.1038/s41551-020-00665-x. Epub 2021 Jan 4. Nat Biomed Eng. 2021. PMID: 33390588 Free PMC article.
Comparison of Proteomic Responses as Global Approach to Antibiotic Mechanism of Action Elucidation.
Senges CHR, Stepanek JJ, Wenzel M, Raatschen N, Ay Ü, Märtens Y, Prochnow P, Vázquez Hernández M, Yayci A, Schubert B, Janzing NBM, Warmuth HL, Kozik M, Bongard J, Alumasa JN, Albada B, Penkova M, Lukežič T, Sorto NA, Lorenz N, Miller RG, Zhu B, Benda M, Stülke J, Schäkermann S, Leichert LI, Scheinpflug K, Brötz-Oesterhelt H, Hertweck C, Shaw JT, Petković H, Brunel JM, Keiler KC, Metzler-Nolte N, Bandow JE. Senges CHR, et al. Antimicrob Agents Chemother. 2020 Dec 16;65(1):e01373-20. doi: 10.1128/AAC.01373-20. Print 2020 Dec 16. Antimicrob Agents Chemother. 2020. PMID: 33046497 Free PMC article.
13 results