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2020 8
2021 2
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Activating Sphingosine-1-phospahte signaling in endothelial cells increases myosin light chain phosphorylation to decrease endothelial permeability thereby inhibiting cancer metastasis.
Chen YC, Dinavahi SS, Feng Q, Gowda R, Ramisetti S, Xia X, LaPenna KB, Chirasani VR, Cho SH, Hafenstein SL, Battu MB, Berg A, Sharma AK, Kirchhausen T, Dokholyan NV, Amin S, He P, Robertson GP. Chen YC, et al. Cancer Lett. 2021 May 28;506:107-119. doi: 10.1016/j.canlet.2021.01.004. Epub 2021 Feb 16. Cancer Lett. 2021. PMID: 33600895 Free PMC article.
Recent progress on cheminformatics approaches to epigenetic drug discovery.
Sessions Z, Sánchez-Cruz N, Prieto-Martínez FD, Alves VM, Santos HP Jr, Muratov E, Tropsha A, Medina-Franco JL. Sessions Z, et al. Drug Discov Today. 2020 Dec;25(12):2268-2276. doi: 10.1016/j.drudis.2020.09.021. Epub 2020 Sep 30. Drug Discov Today. 2020. PMID: 33010481 Free PMC article. Review.
Various miRNAs compensate the role of miR-122 on HCV replication.
Ono C, Fukuhara T, Li S, Wang J, Sato A, Izumi T, Fauzyah Y, Yamamoto T, Morioka Y, Dokholyan NV, Standley DM, Matsuura Y. Ono C, et al. PLoS Pathog. 2020 Jun 23;16(6):e1008308. doi: 10.1371/journal.ppat.1008308. eCollection 2020 Jun. PLoS Pathog. 2020. PMID: 32574204 Free PMC article.
RNA-Puzzles Round IV: 3D structure predictions of four ribozymes and two aptamers.
Miao Z, Adamiak RW, Antczak M, Boniecki MJ, Bujnicki J, Chen SJ, Cheng CY, Cheng Y, Chou FC, Das R, Dokholyan NV, Ding F, Geniesse C, Jiang Y, Joshi A, Krokhotin A, Magnus M, Mailhot O, Major F, Mann TH, Piątkowski P, Pluta R, Popenda M, Sarzynska J, Sun L, Szachniuk M, Tian S, Wang J, Wang J, Watkins AM, Wiedemann J, Xiao Y, Xu X, Yesselman JD, Zhang D, Zhang Y, Zhang Z, Zhao C, Zhao P, Zhou Y, Zok T, Żyła A, Ren A, Batey RT, Golden BL, Huang L, Lilley DM, Liu Y, Patel DJ, Westhof E. Miao Z, et al. RNA. 2020 Aug;26(8):982-995. doi: 10.1261/rna.075341.120. Epub 2020 May 5. RNA. 2020. PMID: 32371455 Free PMC article.
Experimentally-driven protein structure modeling.
Dokholyan NV. Dokholyan NV. J Proteomics. 2020 May 30;220:103777. doi: 10.1016/j.jprot.2020.103777. Epub 2020 Apr 5. J Proteomics. 2020. PMID: 32268219 Free PMC article. Review.
37 results