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Page 1
Enzymatic Pyridine Aromatization during Thiopeptide Biosynthesis.
Rice AJ, Pelton JM, Kramer NJ, Catlin DS, Nair SK, Pogorelov TV, Mitchell DA, Bowers AA. Rice AJ, et al. J Am Chem Soc. 2022 Nov 23;144(46):21116-21124. doi: 10.1021/jacs.2c07377. Epub 2022 Nov 9. J Am Chem Soc. 2022. PMID: 36351243 Free PMC article.
A scalable platform to discover antimicrobials of ribosomal origin.
Ayikpoe RS, Shi C, Battiste AJ, Eslami SM, Ramesh S, Simon MA, Bothwell IR, Lee H, Rice AJ, Ren H, Tian Q, Harris LA, Sarksian R, Zhu L, Frerk AM, Precord TW, van der Donk WA, Mitchell DA, Zhao H. Ayikpoe RS, et al. Nat Commun. 2022 Oct 17;13(1):6135. doi: 10.1038/s41467-022-33890-w. Nat Commun. 2022. PMID: 36253467 Free PMC article.
Enzymatic thioamidation of peptide backbones.
Liu A, Krushnamurthy PH, Subramanya KS, Mitchell DA, Mahanta N. Liu A, et al. Methods Enzymol. 2021;656:459-494. doi: 10.1016/bs.mie.2021.04.010. Epub 2021 May 11. Methods Enzymol. 2021. PMID: 34325795 Free PMC article.
New developments in RiPP discovery, enzymology and engineering.
Montalbán-López M, Scott TA, Ramesh S, Rahman IR, van Heel AJ, Viel JH, Bandarian V, Dittmann E, Genilloud O, Goto Y, Grande Burgos MJ, Hill C, Kim S, Koehnke J, Latham JA, Link AJ, Martínez B, Nair SK, Nicolet Y, Rebuffat S, Sahl HG, Sareen D, Schmidt EW, Schmitt L, Severinov K, Süssmuth RD, Truman AW, Wang H, Weng JK, van Wezel GP, Zhang Q, Zhong J, Piel J, Mitchell DA, Kuipers OP, van der Donk WA. Montalbán-López M, et al. Nat Prod Rep. 2021 Jan 1;38(1):130-239. doi: 10.1039/d0np00027b. Epub 2020 Sep 16. Nat Prod Rep. 2021. PMID: 32935693 Free PMC article. Review.
43 results