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Year Number of Results
2001 1
2002 1
2006 1
2007 3
2008 7
2009 6
2010 8
2011 4
2012 5
2013 3
2014 4
2015 2
2016 1
2017 2
2018 3
2019 1
2020 1
2021 3
2022 1
2023 6
2024 2

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61 results

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Page 1
Directed evolution of genetically encoded LYTACs for cell-mediated delivery.
Yang JL, Yamada-Hunter SA, Labanieh L, Sotillo E, Cheah JS, Roberts DS, Mackall CL, Bertozzi CR, Ting AY. Yang JL, et al. Proc Natl Acad Sci U S A. 2024 Mar 26;121(13):e2320053121. doi: 10.1073/pnas.2320053121. Epub 2024 Mar 22. Proc Natl Acad Sci U S A. 2024. PMID: 38513100 Free PMC article.
Directed Evolution of Genetically Encoded LYTACs for Cell-Mediated Delivery.
Yang JL, Yamada-Hunter SA, Labanieh L, Sotillo E, Cheah JS, Roberts DS, Mackall CL, Ting AY, Bertozzi CR. Yang JL, et al. bioRxiv [Preprint]. 2023 Nov 15:2023.11.14.567117. doi: 10.1101/2023.11.14.567117. bioRxiv. 2023. PMID: 38014030 Free PMC article. Updated. Preprint.
Galectin-3 does not interact with RNA directly.
Peltan EL, Riley NM, Flynn RA, Roberts DS, Bertozzi CR. Peltan EL, et al. Glycobiology. 2024 Mar 19;34(1):cwad076. doi: 10.1093/glycob/cwad076. Glycobiology. 2024. PMID: 37815932
Designed Endocytosis-Triggering Proteins mediate Targeted Degradation.
Huang B, Abedi M, Ahn G, Coventry B, Sappington I, Wang R, Schlichthaerle T, Zhang JZ, Wang Y, Goreshnik I, Chiu CW, Chazin-Gray A, Chan S, Gerben S, Murray A, Wang S, O'Neill J, Yeh R, Misquith A, Wolf A, Tomasovic LM, Piraner DI, Gonzalez MJD, Bennett NR, Venkatesh P, Satoe D, Ahlrichs M, Dobbins C, Yang W, Wang X, Vafeados D, Mout R, Shivaei S, Cao L, Carter L, Stewart L, Spangler JB, Bernardes GJL, Roybal KT, Greisen P Jr, Li X, Bertozzi C, Baker D. Huang B, et al. bioRxiv [Preprint]. 2023 Sep 20:2023.08.19.553321. doi: 10.1101/2023.08.19.553321. bioRxiv. 2023. PMID: 37781607 Free PMC article. Preprint.
The human disease gene LYSET is essential for lysosomal enzyme transport and viral infection.
Richards CM, Jabs S, Qiao W, Varanese LD, Schweizer M, Mosen PR, Riley NM, Klüssendorf M, Zengel JR, Flynn RA, Rustagi A, Widen JC, Peters CE, Ooi YS, Xie X, Shi PY, Bartenschlager R, Puschnik AS, Bogyo M, Bertozzi CR, Blish CA, Winter D, Nagamine CM, Braulke T, Carette JE. Richards CM, et al. Science. 2022 Oct 7;378(6615):eabn5648. doi: 10.1126/science.abn5648. Epub 2022 Oct 7. Science. 2022. PMID: 36074821 Free PMC article.
The CD22-IGF2R interaction is a therapeutic target for microglial lysosome dysfunction in Niemann-Pick type C.
Pluvinage JV, Sun J, Claes C, Flynn RA, Haney MS, Iram T, Meng X, Lindemann R, Riley NM, Danhash E, Chadarevian JP, Tapp E, Gate D, Kondapavulur S, Cobos I, Chetty S, Pașca AM, Pașca SP, Berry-Kravis E, Bertozzi CR, Blurton-Jones M, Wyss-Coray T. Pluvinage JV, et al. Sci Transl Med. 2021 Dec;13(622):eabg2919. doi: 10.1126/scitranslmed.abg2919. Epub 2021 Dec 1. Sci Transl Med. 2021. PMID: 34851695 Free PMC article.
61 results