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In premenopausal women with idiopathic osteoporosis, lower bone formation rate is associated with higher body fat and higher IGF-1.
Goetz TG, Nair N, Shiau S, Recker RR, Lappe JM, Dempster DW, Zhou H, Zhao B, Guo X, Shen W, Nickolas TL, Kamanda-Kosseh M, Bucovsky M, Stubby J, Shane E, Cohen A. Goetz TG, et al. Osteoporos Int. 2022 Mar;33(3):659-672. doi: 10.1007/s00198-021-06196-8. Epub 2021 Oct 19. Osteoporos Int. 2022. PMID: 34665288 Free PMC article.
Effect of Teriparatide on Bone Remodeling and Density in Premenopausal Idiopathic Osteoporosis: A Phase II Trial.
Cohen A, Shiau S, Nair N, Recker RR, Lappe JM, Dempster DW, Nickolas TL, Zhou H, Agarwal S, Kamanda-Kosseh M, Bucovsky M, Williams JM, McMahon DJ, Stubby J, Shane E. Cohen A, et al. J Clin Endocrinol Metab. 2020 Oct 1;105(10):e3540-56. doi: 10.1210/clinem/dgaa489. J Clin Endocrinol Metab. 2020. PMID: 32876328 Free PMC article. Clinical Trial.